20(S)‐protopanaxadiol induces apoptosis in human umbilical vein endothelial cells by activating the PERK‐eIF2alpha‐ATF4 signaling pathway
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.27785
Abstract: 20(S)‐protopanaxadiol (PPD)‐type ginsenosides are generally believed to be the most pharmacologically active components of Panax ginseng. These compounds induce apoptotic cell death in various cancer cells, which suggests that they have anti‐cancer activity. Anti‐angiogenesis is… read more here.
Keywords: ppd; human umbilical; perk; expression ... See more keywords
HomeoboxC6 affects the apoptosis of human vascular endothelial cells and is involved in atherosclerosis
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.29974
Abstract: Apoptosis of vascular endothelial cells (VECs) is highly important in the occurrence and development of atherosclerosis (AS). HomeboxC6 (HOXC6) is expressed in higher levels in multiple malignant tissues, and it influences the malignant biological behavior… read more here.
Keywords: vascular endothelial; expression; endothelial cells; apoptosis human ... See more keywords
Perfluorooctanoic acid exposure increases both proliferation and apoptosis of human placental trophoblast cells mediated by ER stress-induced ROS or UPR pathways.
Sign Up to like & getrecommendations! Published in 2022 at "Ecotoxicology and environmental safety"
DOI: 10.1016/j.ecoenv.2022.113508
Abstract: Perfluorooctanoate acid (PFOA) is a highly persistent and widespread chemical in the environment. PFOA serum levels in pregnant women are positively associated with an increased risk of placenta-related disorders. However, the mechanism of PFOA cytotoxicity… read more here.
Keywords: apoptosis human; stress; apoptosis; proliferation ... See more keywords
Epigallocatechin-3-gallate attenuates microcystin-LR-induced apoptosis in human umbilical vein endothelial cells through activation of the NRF2/HO-1 pathway.
Sign Up to like & getrecommendations! Published in 2018 at "Environmental pollution"
DOI: 10.1016/j.envpol.2018.04.038
Abstract: Our previous study showed that the tea extract, epigallocatechin-3-gallate (EGCG), protects against microcystin-LR (MC-LR) -mediated apoptosis of human umbilical vein endothelial cells (HUVECs); however, the mechanism underlying MC-LR-induced HUVEC apoptosis remains incompletely understood. In this… read more here.
Keywords: huvec apoptosis; apoptosis; epigallocatechin gallate; human umbilical ... See more keywords
Effects of microRNA-146a on the proliferation and apoptosis of human osteochondrocytes by targeting TRAF6 through the NF- κB signalling pathway
Sign Up to like & getrecommendations! Published in 2017 at "Bioscience Reports"
DOI: 10.1042/bsr20170180
Abstract: MicroRNAs are important cellular mediators of mRNA degradation and translation repression, which in turn can have an impact on various processes and, if their function is perturbed, can cause disease. Here, we summarize the recent… read more here.
Keywords: proliferation apoptosis; 146a proliferation; proliferation; microrna 146a ... See more keywords
Baicalin induces apoptosis in human osteosarcoma cell through ROS-mediated mitochondrial pathway
Sign Up to like & getrecommendations! Published in 2018 at "Natural Product Research"
DOI: 10.1080/14786419.2017.1359173
Abstract: Abstract Baicalin is extracted from a traditional Chinese herb, Scutellaria baicalensis. In this study, the anticancer activity and underlying mechanisms of baicalin towards human osteosarcoma cell (HOS) were investigated. Baicalin could inhibit HOS cell proliferation… read more here.
Keywords: baicalin; osteosarcoma cell; apoptosis human; cell ... See more keywords
Leptin attenuates hypoxia‐induced apoptosis in human periodontal ligament cells via the reactive oxygen species–hypoxia‐inducible factor‐1α pathway
Sign Up to like & getrecommendations! Published in 2021 at "Experimental Physiology"
DOI: 10.1113/ep089324
Abstract: What is the central question of this study? Does leptin have an effect on hypoxia‐induced apoptosis in human periodontal ligament cells (hPDLCs), and what is the potential underlying mechanism? What is the main finding and… read more here.
Keywords: apoptosis human; leptin; hypoxia induced; human periodontal ... See more keywords
The Molecular Mechanism of Long Non-Coding RNA (LncRNA) Regulation of Notch Signaling in Glucose-Induced Apoptosis of Human Retinal Vascular Endothelial Cell.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of biomedical nanotechnology"
DOI: 10.1166/jbn.2022.3291
Abstract: Diabetes, a global health concern, affects the health of more than 500 million adults. The absence of Notch protein can cause an imbalance in the retinal vascular environment and cause retinal vascular disease. Long noncoding… read more here.
Keywords: apoptosis human; rna lncrna; retinal vascular; notch ... See more keywords
Alpha-1 antitrypsin inhibits formaldehyde-induced apoptosis of human peritoneal mesothelial cells
Sign Up to like & getrecommendations! Published in 2020 at "Peritoneal Dialysis International"
DOI: 10.1177/0896860819887288
Abstract: Background: The alpha-1 antitrypsin (AAT) protein has an important role in the anti-inflammatory and apoptotic response. AAT inhibits not only serine proteases but also cysteine and aspartic proteases. Apoptosis results from the sequential activation of… read more here.
Keywords: formaldehyde induced; apoptosis; induced apoptosis; aat ... See more keywords
Protective effects of upregulated HO-1 gene against the apoptosis of human retinal pigment epithelial cells in vitro.
Sign Up to like & getrecommendations! Published in 2021 at "International journal of ophthalmology"
DOI: 10.18240/ijo.2021.05.03
Abstract: AIM To investigate the protective effect of heme oxygenase-1 (HO-1) against H2O2-induced apoptosis in human ARPE-19 cells. METHODS The lentiviral vector expressing HO-1 was prepared and transfected into apoptotic ARPE-19 cells induced by H2O2. Functional… read more here.
Keywords: arpe cells; apoptosis; h2o2 induced; effects upregulated ... See more keywords
Gadodiamide Induced Autophagy and Apoptosis in Human Keratinocytes
Sign Up to like & getrecommendations! Published in 2022 at "In Vivo"
DOI: 10.21873/invivo.12743
Abstract: Background/Aim: Gadolinium has been reported to cause liver lobular necrosis and nephrogenic systemic fibrosis. However, its toxicity to the skin remains unknown. This study aimed to investigate the effect of a high dose of gadolinium-based… read more here.
Keywords: apoptosis human; human keratinocytes; autophagy apoptosis; apoptosis ... See more keywords