Articles with "apoptosis inflammation" as a keyword



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Ameliorative effect of docosahexaenoic acid on hepatocyte apoptosis and inflammation induced by oleic acid in grass carp, Ctenopharyngodon idella

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Published in 2019 at "Fish Physiology and Biochemistry"

DOI: 10.1007/s10695-019-00623-8

Abstract: Our previous study has shown that overload of lipid accumulation results in cell apoptosis and inflammation in grass carp (Ctenopharyngodon idella). In this study, we investigated the potential protective effects of docosahexaenoic acid (DHA) on… read more here.

Keywords: grass carp; apoptosis inflammation; dha; inflammation ... See more keywords
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Inhibition of TNFR1 Attenuates LPS Induced Apoptosis and Inflammation in Human Nucleus Pulposus Cells by Regulating the NF-KB and MAPK Signalling Pathway.

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Published in 2021 at "Neurochemical research"

DOI: 10.1007/s11064-021-03278-1

Abstract: Intervertebral disc degeneration (IDD) is accompanied by nucleus pulposus (NP) cell apoptosis, inflammation, and extracellular matrix degradation. Tumour necrosis factor receptor 1 (TNFR1) is a receptor of TNF-α, and is deeply involved in the processes… read more here.

Keywords: tnfr1; mapk signalling; apoptosis inflammation;
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Human Umbilical Cord Mesenchymal Stem Cells Improve Ovarian Function in Chemotherapy-Induced Premature Ovarian Failure Mice Through Inhibiting Apoptosis and Inflammation via a Paracrine Mechanism

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Published in 2021 at "Reproductive Sciences"

DOI: 10.1007/s43032-021-00499-1

Abstract: Human umbilical cord mesenchymal stem cell (UC-MSC) application is a promising arising therapy for the treatment of premature ovarian failure (POF). However, little is known about the inflammation regulatory effects of human umbilical cord MSCs… read more here.

Keywords: umbilical cord; inflammation; human umbilical; chemotherapy induced ... See more keywords
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Esmolol reduces apoptosis and inflammation in early sepsis rats with abdominal infection

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Published in 2017 at "American Journal of Emergency Medicine"

DOI: 10.1016/j.ajem.2017.04.056

Abstract: Background: Esmolol is a highly selective beta 1 receptor blocker with various effects such as slowing heart rate, lowering blood pressure and reducing myocardial oxygen consumption. However, few studies have reported the use of beta… read more here.

Keywords: sepsis; early sepsis; group; apoptosis inflammation ... See more keywords
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miR-145-5p is associated with smoke-related chronic obstructive pulmonary disease via targeting KLF5.

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Published in 2019 at "Chemico-biological interactions"

DOI: 10.1016/j.cbi.2019.01.011

Abstract: Increasing evidence illustrate that dysregulation of microRNAs (miRNAs) is involved in the pathogenesis of chronic obstructive pulmonary disease (COPD), which is mainly resulted from cigarette smoke (CS) exposure. However, the role of miR-145-5p in CS-mediated… read more here.

Keywords: chronic obstructive; mir 145; obstructive pulmonary; pulmonary disease ... See more keywords
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Herbicide exposure induces apoptosis, inflammation, immune modulation and suppression of cell survival mechanism in murine model

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Published in 2017 at "RSC Advances"

DOI: 10.1039/c6ra27883c

Abstract: The lymphatic organ, the spleen, is of immense immunological importance as it is the largest blood filter in the mammalian system. The objective of the current study is to explore the detrimental cellular and sub-cellular… read more here.

Keywords: apoptosis inflammation; model; cell; herbicide exposure ... See more keywords
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LncRNA HOTAIR modulates chondrocyte apoptosis and inflammation in osteoarthritis via regulating miR‐1277‐5p/SGTB axis

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Published in 2021 at "Wound Repair and Regeneration"

DOI: 10.1111/wrr.12908

Abstract: Osteoarthritis (OA) is a common degenerative joint disease in the elderly. This study aimed to investigate the role and mechanism of lncRNA HOX transcript antisense RNA (HOTAIR) in lipopolysaccharide (LPS)‐treated chondrocytes in OA. CHON‐001 chondrocytes… read more here.

Keywords: apoptosis inflammation; hotair; sgtb; mir 1277 ... See more keywords
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Notoginsenoside R1 upregulates miR-221-3p expression to alleviate ox-LDL-induced apoptosis, inflammation, and oxidative stress by inhibiting the TLR4/NF-κB pathway in HUVECs

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Published in 2020 at "Brazilian Journal of Medical and Biological Research"

DOI: 10.1590/1414-431x20209346

Abstract: Atherosclerosis (AS) is a common vascular disease, which can cause apoptosis of vascular endothelial cells. Notoginsenoside R1 (NGR1) is considered an anti-AS drug. MicroRNAs (miRNAs) are believed to play a vital role in cell apoptosis… read more here.

Keywords: mir 221; expression; inflammation oxidative; 221 expression ... See more keywords
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Isolevuglandins Scavenger Ameliorates Myocardial Ischemic Injury by Suppressing Oxidative Stress, Apoptosis, and Inflammation

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Published in 2022 at "Frontiers in Cell and Developmental Biology"

DOI: 10.3389/fcell.2022.836035

Abstract: Augmented levels of reactive isolevuglandins (IsoLGs) are responsible for cardiovascular diseases. The role of IsoLGs in myocardial infarction (MI) remains elusive. Here we explored the effect of IsoLGs scavenger 2-hydroxybenzylamine (2-HOBA) in post-infarction cardiac repair.… read more here.

Keywords: stress apoptosis; injury; oxidative stress; apoptosis inflammation ... See more keywords
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Granzyme B in Inflammatory Diseases: Apoptosis, Inflammation, Extracellular Matrix Remodeling, Epithelial-to-Mesenchymal Transition and Fibrosis

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Published in 2020 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2020.587581

Abstract: Inflammation is strictly interconnected to anti-inflammatory mechanisms to maintain tissue homeostasis. The disruption of immune homeostasis can lead to acute and chronic inflammatory diseases, as cardiovascular, pulmonary, metabolic diseases and cancer. The knowledge of the… read more here.

Keywords: fibrosis; extracellular matrix; inflammatory diseases; inflammatory ... See more keywords
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HTR2B and SLC5A3 Are Specific Markers in Age-Related Osteoarthritis and Involved in Apoptosis and Inflammation of Osteoarthritis Synovial Cells

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Published in 2021 at "Frontiers in Molecular Biosciences"

DOI: 10.3389/fmolb.2021.691602

Abstract: Objective: Osteoarthritis (OA) is a heterogeneous age-related disease, which is badly difficult to cure due to its complex regulatory networks of pathogenesis. This study explored OA-specific genes in synovial tissues and validated their roles on… read more here.

Keywords: age related; htr2b slc5a3; apoptosis inflammation; synovial cells ... See more keywords