The antagonistic effect of melatonin on TBBPA‐induced apoptosis and necroptosis via PTEN/PI3K/AKT signaling pathway in swine testis cells
Sign Up to like & getrecommendations! Published in 2022 at "Environmental Toxicology"
DOI: 10.1002/tox.23595
Abstract: Tetrabromobisphenol A (TBBPA) is a widely used industrial brominated flame retardant, which can endanger animal and human health, including cytotoxicity, endocrine disruption, reproductive toxicity and so on. Melatonin (MT) is a noteworthy free radical scavenger… read more here.
Keywords: necroptosis; pi3k akt; tbbpa; expression ... See more keywords
Polystyrene microplastics induce apoptosis and necroptosis in swine testis cells via ROS/MAPK/HIF1α pathway
Sign Up to like & getrecommendations! Published in 2022 at "Environmental Toxicology"
DOI: 10.1002/tox.23611
Abstract: Microplastics (MPs) generally refer to the plastic fragments or particles smaller than 5 mm in diameter, which are closely concerned due to their widespread presence in the environment. Recent studies have shown that MPs have a… read more here.
Keywords: hif1; via ros; polystyrene microplastics; apoptosis necroptosis ... See more keywords
Curcumin Targets Both Apoptosis and Necroptosis in Acidity-Tolerant Prostate Carcinoma Cells
Sign Up to like & getrecommendations! Published in 2021 at "BioMed Research International"
DOI: 10.1155/2021/8859181
Abstract: Objective Curcumin, a major bioactive curcuminoid derived from the rhizome of Curcuma longa, is known to have anticancer potential and is still under investigation. In this study, we investigated the cytotoxic mechanism(s) of curcumin against… read more here.
Keywords: prostate carcinoma; apoptosis necroptosis; acidity tolerant; curcumin ... See more keywords
DHEA protects mitochondria against dual modes of apoptosis and necroptosis in human granulosa HO23 cells.
Sign Up to like & getrecommendations! Published in 2017 at "Reproduction"
DOI: 10.1530/rep-17-0016
Abstract: Because ovarian granulosa cells are essential for oocyte maturation and development, we validated human granulosa HO23 cells to evaluate the ability of the DHEA to prevent cell death after starvation. The present study was aimed… read more here.
Keywords: granulosa; apoptosis necroptosis; ho23 cells; granulosa ho23 ... See more keywords
Targeting Cell Death: Pyroptosis, Ferroptosis, Apoptosis and Necroptosis in Osteoarthritis
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2021.789948
Abstract: New research has shown that the development of osteoarthritis (OA) is regulated by different mechanisms of cell death and types of cytokines. Therefore, elucidating the mechanism of action among various cytokines, cell death processes and… read more here.
Keywords: osteoarthritis; cell death; pyroptosis; death ... See more keywords
The PANoptosome: A Deadly Protein Complex Driving Pyroptosis, Apoptosis, and Necroptosis (PANoptosis)
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2020.00238
Abstract: Programmed cell death is regulated by evolutionarily conserved pathways that play critical roles in development and the immune response. A newly recognized pathway for proinflammatory programmed cell death called PANoptosis is controlled by a recently… read more here.
Keywords: panoptosis; protein complex; apoptosis necroptosis; pyroptosis apoptosis ... See more keywords
Concurrent induction of apoptosis and necroptosis in apigenin‑treated malignant mesothelioma cells: Reversal of Warburg effect through Akt inhibition and p53 upregulation
Sign Up to like & getrecommendations! Published in 2023 at "Oncology Reports"
DOI: 10.3892/or.2023.8548
Abstract: A high dependence on aerobic glycolysis, known as the Warburg effect, is one of the metabolic features exhibited by tumor cells. Therefore, targeting glycolysis is becoming a very promising strategy for the development of anticancer… read more here.
Keywords: mesothelioma cells; apigenin; warburg effect; malignant mesothelioma ... See more keywords
Do pyroptosis, apoptosis, and necroptosis (PANoptosis) exist in cerebral ischemia? Evidence from cell and rodent studies
Sign Up to like & getrecommendations! Published in 2022 at "Neural Regeneration Research"
DOI: 10.4103/1673-5374.331539
Abstract: Some scholars have recently developed the concept of PANoptosis in the study of infectious diseases where pyroptosis, apoptosis and necroptosis act in consort in a multimeric protein complex, PANoptosome. This allows all the components of… read more here.
Keywords: pyroptosis apoptosis; ischemia; panoptosis; apoptosis necroptosis ... See more keywords
Synergistic anticancer activity of resveratrol in combination with docetaxel in prostate carcinoma cells
Sign Up to like & getrecommendations! Published in 2021 at "Nutrition Research and Practice"
DOI: 10.4162/nrp.2021.15.1.12
Abstract: BACKGROUND/OBJECTIVES The study was conducted to investigate the efficacy of the combination treatment of phytochemical resveratrol and the anticancer drug docetaxel (DTX) on prostate carcinoma LNCaP cells, including factors related to detailed cell death mechanisms.… read more here.
Keywords: combination; resveratrol; prostate carcinoma; apoptosis necroptosis ... See more keywords
Effect of IRAK1 on Apoptosis and Necroptosis of Hepatoma Cell Line SK-Hep1
Sign Up to like & getrecommendations! Published in 2019 at "Chinese Medicine"
DOI: 10.4236/cm.2019.101003
Abstract: Interleukin I receptor associated kinase 1 (IRAK1) is a downstream signal molecule of activated MyD88 recruitment, which can activate Fas associated death domain protein (FADD) to induce apoptosis. IRAK1 can also activate tumor necrosis factor-related… read more here.
Keywords: hep1; irak1 apoptosis; necroptosis; apoptosis necroptosis ... See more keywords