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   Articles with "apoptosis oxidative" as a keyword



Apoptosis oxidative damage‐mediated and antiproliferative effect of selenylated imidazo[1,2‐a]pyridines on hepatocellular carcinoma HepG2 cells and in vivo

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recommendations! Published in 2020 at "Journal of Biochemical and Molecular Toxicology"

DOI: 10.1002/jbt.22663

Abstract: Imidazo[1,2‐a]pyridines (IP) and organoselenium compounds have been widely exploited in medicinal chemistry due to their pharmacological activities. Hepatocellular carcinoma (HCC) has few treatment options, and unfortunately, the prognosis is poor. Thus, the development of novel… read more here.

Keywords: hepatocellular carcinoma; cells vivo; apoptosis oxidative; hepg2 cells ... See more keywords

Up‐Regulation of miR‐30b‐3p by Krüppel‐Like Factor 5 Induces the Apoptosis and Oxidative Stress in Sow Ovarian Granulosa Cells Through Inhibiting SMAD3 and SOD2

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recommendations! Published in 2025 at "Journal of Cellular Physiology"

DOI: 10.1002/jcp.70103

Abstract: MicroRNAs (miRNAs) have been demonstrated to be involved in various cellular biological processes. However, their impacts on apoptosis and oxidative stress in ovarian granulosa cells (GC) remain largely unknown. Here, we identified that miR‐30b was… read more here.

Keywords: sow; oxidative stress; mir 30b; gcs ... See more keywords

Apoptosis, oxidative stress and genotoxicity in developing zebrafish after aluminium exposure.

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recommendations! Published in 2021 at "Aquatic toxicology"

DOI: 10.1016/j.aquatox.2021.105872

Abstract: Aluminium is a non-essential metal and potentially toxic to organisms whose environmental concentration increases due to pollution. In our previous studies, the behavioral changes induced by aluminium were already shown on zebrafish, a model organism… read more here.

Keywords: apoptosis oxidative; aluminium; stress genotoxicity; concentration ... See more keywords

SIRT6 protects vascular endothelial cells from angiotensin II-induced apoptosis and oxidative stress by promoting the activation of Nrf2/ARE signaling.

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recommendations! Published in 2019 at "European journal of pharmacology"

DOI: 10.1016/j.ejphar.2019.172516

Abstract: Angiotensin II (Ang II) is a vasoactive peptide that elevates arterial blood pressure and leads to hypertension. Ang II has been reported to induce endothelial dysfunction by induction of apoptosis and oxidative stress in vascular… read more here.

Keywords: apoptosis oxidative; vascular endothelial; induced apoptosis; endothelial cells ... See more keywords

Dipeptidyl-peptidase 3 protects oxygen-glucose deprivation/reoxygenation-injured hippocampal neurons by suppressing apoptosis, oxidative stress and inflammation via modulation of Keap1/Nrf2 signaling.

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recommendations! Published in 2021 at "International immunopharmacology"

DOI: 10.1016/j.intimp.2021.107595

Abstract: Dipeptidyl-peptidase 3 (DPP3) plays a key role in regulating apoptosis, oxidative stress and inflammation under various pathological conditions, however, whether DPP3 regulates apoptosis and oxidative stress in neurons undergoing cerebral ischemia/reperfusion injury has not yet… read more here.

Keywords: apoptosis oxidative; dpp3; stress inflammation; oxidative stress ... See more keywords
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AAV9-IGF1 protects TDP-25 cells from apoptosis and oxidative stress partly via up-regulating the expression of VEGF in vitro

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recommendations! Published in 2017 at "Neuroscience Letters"

DOI: 10.1016/j.neulet.2017.01.009

Abstract: Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease lacking of curable treatments to date. Adeno-associated virus (AAV) vectors make gene therapy an effective strategy in treating neurological disorders. Despite Kaspar and colleagues have showed… read more here.

Keywords: apoptosis oxidative; cells apoptosis; tdp cells; expression ... See more keywords

LncRNA KCNQ1OT1 promotes apoptosis and oxidative stress of human lens epithelial cells through epigenetic regulation of WRN.

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recommendations! Published in 2022 at "Current eye research"

DOI: 10.1080/02713683.2022.2026975

Abstract: PURPOSE Long non-coding RNA KCNQ1OT1 is fundamental to age-related cataract (ARC), whereas the underlying mechanism is still unknown. Here, we explored the possible mechanism of KCNQ1OT1 in ARC. METHODS The expression of KCNQ1OT1 in ARC… read more here.

Keywords: wrn; apoptosis oxidative; sra01 cells; oxidative stress ... See more keywords

TYRP1 Protects Against the Apoptosis and Oxidative Stress of Retinal Ganglion Cells by Binding to PMEL.

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recommendations! Published in 2022 at "Ocular immunology and inflammation"

DOI: 10.1080/09273948.2022.2081862

Abstract: OBJECTIVES This research aimed to dissect the function of TYRP1 and PMEL in glaucomatous animal and cell models. METHODS A chronic ocular hypertension (COH) rat model was induced in the right eyes of rats through… read more here.

Keywords: tyrp1; oxidative stress; apoptosis oxidative; pmel ... See more keywords

Treatment with melatonin and selenium attenuates docetaxel‐induced apoptosis and oxidative injury in kidney and testes of mice

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recommendations! Published in 2019 at "Andrologia"

DOI: 10.1111/and.13320

Abstract: Docetaxel (DTX) has been used in cancer treatments for several decades, but it results in many adverse apoptotic effects through excessive production of reactive oxygen species (ROS) in some tissue including the kidney and testes.… read more here.

Keywords: apoptosis oxidative; dtx; induced apoptosis; kidney testes ... See more keywords

Ursodeoxycholic acid: Effects on hepatic unfolded protein response, apoptosis and oxidative stress in morbidly obese patients

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recommendations! Published in 2018 at "Liver International"

DOI: 10.1111/liv.13562

Abstract: Ursodeoxycholic acid (UDCA) is a secondary hydrophilic bile acid (BA) used as therapy for a range of hepatobiliary diseases. Its efficacy in non‐alcoholic fatty liver disease (NAFLD) is still under debate. Here, we aimed to… read more here.

Keywords: apoptosis oxidative; morbidly obese; ursodeoxycholic acid; stress morbidly ... See more keywords

Upregulated IGFBP3 with Aging Is Involved in Modulating Apoptosis, Oxidative Stress, and Fibrosis: A Target of Age-Related Erectile Dysfunction

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recommendations! Published in 2022 at "Oxidative Medicine and Cellular Longevity"

DOI: 10.1155/2022/6831779

Abstract: Aging has been deemed the primary factor in erectile dysfunction (ED). Herein, age-related changes in the erectile response and histomorphology were detected, and the relationship between aging and ED was investigated based on gene expression… read more here.

Keywords: apoptosis; age related; erectile dysfunction; apoptosis oxidative ... See more keywords