3,3′,4,4′,5‐Pentachlorobiphenyl influences mitochondrial apoptosis pathway in granulosa cells
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.28801
Abstract: 3,3′,4,4′,5‐Polychlorinated biphenyl (PCB126) is a persistent organic environmental pollutant which can affect various biological activities of organisms, such as immunity, neurological function, and reproduction. In our study, we aimed to investigate the effects of PCB126… read more here.
Keywords: granulosa cells; mitochondrial apoptosis; apoptosis; gcs ... See more keywords
Novel NO-releasing scopoletin derivatives induce cell death via mitochondrial apoptosis pathway and cell cycle arrest.
Sign Up to like & getrecommendations! Published in 2020 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2020.112386
Abstract: A series of phenylsulfonyfuroxan-based NO-releasing scopoletin derivatives were designed and synthesized in the study. All target compounds showed significantly improved antiproliferative activity against four cancer cell lines (MDA-MB-231, MCF-7, HepG2 and A459) and lower cytotoxicity… read more here.
Keywords: mitochondrial apoptosis; mda 231; scopoletin derivatives; releasing scopoletin ... See more keywords
Jujing Zhuyu decoction inhibits apoptosis in rats with asthenozoospermia by regulating the mitochondrial apoptosis pathway
Sign Up to like & getrecommendations! Published in 2022 at "Andrologia"
DOI: 10.1111/and.14632
Abstract: Jujing Zhuyu decoction (JZD) is a traditional Chinese medicine that effectively improves sperm motility. However, the molecular mechanism of JZD on asthenozoospermia still remains unknown. In this study, we investigated the effect of JZD on… read more here.
Keywords: apoptosis; mitochondrial apoptosis; jzd jzd; model ... See more keywords
Pattern Recognition Receptors of Nucleic Acids Can Cause Sublethal Activation of the Mitochondrial Apoptosis Pathway during Viral Infection
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Virology"
DOI: 10.1128/jvi.01212-22
Abstract: A contribution of the mitochondrial apoptosis apparatus, in the absence of cell death, to the reaction of nonprofessional immune cells to viruses is suggested to play a role as a broad alert system of an… read more here.
Keywords: recognition; cell; apoptosis; mitochondrial apoptosis ... See more keywords
Asiatic Acid Alleviates Myocardial Ischemia-Reperfusion Injury by Inhibiting the ROS-Mediated Mitochondria-Dependent Apoptosis Pathway
Sign Up to like & getrecommendations! Published in 2022 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2022/3267450
Abstract: Myocardial ischemia-reperfusion injury (MIRI) is a major cause of heart failure in patients with coronary heart disease (CHD). Mitochondrial dysfunction is the crucial factor of MIRI; oxidative stress caused by mitochondrial reactive oxygen species (ROS)… read more here.
Keywords: dependent apoptosis; mitochondria dependent; reperfusion; medicine ... See more keywords
Abstract 1802: Apoptosis pathway-focused gene expression profiling of a novel VEGFR2 inhibitor
Sign Up to like & getrecommendations! Published in 2017 at "Cancer Research"
DOI: 10.1158/1538-7445.am2017-1802
Abstract: Sprouting of the new blood vessel (angiogenesis) is fundamental to tumor growth, invasion, and metastatic dissemination. Vascular endothelial growth factor (VEGF), an endothelial cell-specific mitogen, promotes cell survival via opposing apoptosis. On the other hand,… read more here.
Keywords: apoptosis; pathway focused; pathway; expression ... See more keywords
Evodiamine suppresses the progression of non-small cell lung carcinoma via endoplasmic reticulum stress-mediated apoptosis pathway in vivo and in vitro
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Immunopathology and Pharmacology"
DOI: 10.1177/03946320221086079
Abstract: Background Evodiamine (EVO) is one of the major components isolated from Evodia rutaecarpa (Juss.). Recent studies have shown that EVO has an anti-cancer effect. However, the pharmacological mechanism by which EVO impacts cancer is still… read more here.
Keywords: cell; mediated apoptosis; apoptosis; tumor ... See more keywords
Nd2O3 Nanoparticles Induce Toxicity and Cardiac/Cerebrovascular Abnormality in Zebrafish Embryos via the Apoptosis Pathway
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Nanomedicine"
DOI: 10.2147/ijn.s220785
Abstract: Introduction Rare-earth nanoparticles in the environment and human body pose a potential threat to human health. Although toxic effects of rare-earth nanoparticles have been extensively studied, the effects on the early development are not well… read more here.
Keywords: cardiac cerebrovascular; development; nd2o3 nanoparticles; embryos ... See more keywords
Targeting the Intrinsic Apoptosis Pathway: A Window of Opportunity for Prostate Cancer
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DOI: 10.3390/cancers14010051
Abstract: Simple Summary Prostate cancer treatment has improved over the last 20 years; despite this, approximately 33,000 men died from the disease in the United States in 2020. In view of this, new treatment options are… read more here.
Keywords: cancer; apoptosis; intrinsic apoptosis; apoptosis pathway ... See more keywords
Ilimaquinone (Marine Sponge Metabolite) Induces Apoptosis in HCT-116 Human Colorectal Carcinoma Cells via Mitochondrial-Mediated Apoptosis Pathway
Sign Up to like & getrecommendations! Published in 2022 at "Marine Drugs"
DOI: 10.3390/md20090582
Abstract: Ilimaquinone (IQ), a metabolite found in marine sponges, has been reported to have a number of biological properties, including potential anticancer activity against colon cancer. However, no clear understanding of the precise mechanism involved is… read more here.
Keywords: mediated apoptosis; apoptosis; mitochondrial mediated; hct 116 ... See more keywords
Targeting the mitochondrial apoptosis pathway by a newly synthesized COX-2 inhibitor in pediatric ALL lymphocytes.
Sign Up to like & getrecommendations! Published in 2018 at "Future medicinal chemistry"
DOI: 10.4155/fmc-2018-0032
Abstract: AIM Acute lymphoblastic leukemia (ALL) is known as a barely curable malignancy. Particular mutations involved in apoptosis may have a main role in the onset of ALL in the pediatric patients. It has been proven… read more here.
Keywords: inhibitor; apoptosis; newly synthesized; targeting mitochondrial ... See more keywords