Articles with "apoptosis related" as a keyword



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Analysis of anti‐apoptotic PVT1 oncogene and apoptosis‐related proteins (p53, Bcl2, PD‐1, and PD‐L1) expression in thyroid carcinoma

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Published in 2022 at "Journal of Clinical Laboratory Analysis"

DOI: 10.1002/jcla.24390

Abstract: An aberrant expression of long non‐coding RNA PVT1 has been associated with apoptosis in various cancer types. We aimed to explore the PVT1 and four apoptosis‐related proteins (p53, Bcl2, and PD‐1/PD‐L1) signature in thyroid cancer… read more here.

Keywords: p53 bcl2; related proteins; proteins p53; expression ... See more keywords
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Paraoxon-induced damage in rat hippocampus is associated with alterations in the expression of apoptosis-related proteins.

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Published in 2020 at "Pesticide biochemistry and physiology"

DOI: 10.1016/j.pestbp.2020.104580

Abstract: To determine the possible role of apoptosis in the development of paraoxon-induced brain damage, we evaluated expression of apoptosis-related proteins, the extent of neuronal damage, and activation of astrocytes in rat hippocampus. Adult male Wistar… read more here.

Keywords: hippocampus; expression apoptosis; related proteins; apoptosis related ... See more keywords
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Identification of apoptosis-related genes in erythrocytes of broiler chickens and their response to thiram-induced tibial dyschondroplasia and recombinant glutathione-S-transferase A3 protein.

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Published in 2018 at "Research in veterinary science"

DOI: 10.1016/j.rvsc.2018.08.001

Abstract: Thiram, a carbamate pesticide, is known to induce tibial dyschondroplasia (TD) in broiler chickens. This study used a thiram-induced TD model to explore whether apoptosis-related genes were expressed in erythrocytes of broiler chickens and the… read more here.

Keywords: protein; apoptosis related; related genes; expression ... See more keywords
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Apoptosis-related genes induced in response to ketamine during early life stages of zebrafish.

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Published in 2017 at "Toxicology letters"

DOI: 10.1016/j.toxlet.2017.07.888

Abstract: Increasing evidence supports that ketamine, a widely used anaesthetic, potentiates apoptosis during development through the mitochondrial pathway of apoptosis. Defects in the apoptotic machinery can cause or contribute to the developmental abnormalities previously described in… read more here.

Keywords: ketamine; exposure; apoptosis related; related genes ... See more keywords
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An activatable DNA nanodevice for correlated imaging of apoptosis-related dual proteins.

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Published in 2022 at "Nanoscale"

DOI: 10.1039/d2nr00537a

Abstract: Apoptosis plays an important role in the life cycle of multicellular organisms. The development of techniques for sensitive monitoring of apoptosis-related key molecules can be used to assess not only disease progression but also its… read more here.

Keywords: apoptosis related; activatable dna; related dual; apoptosis ... See more keywords
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Silencing Cardiac Troponin I-Interacting Kinase Reduces Lipopolysaccharide-Induced Sepsis-Induced Myocardial Dysfunction in Rat by Regulating Apoptosis-Related Proteins

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Published in 2021 at "BioMed Research International"

DOI: 10.1155/2021/5520051

Abstract: The aim of this study was to investigate the effect of cardiac troponin I-interacting kinase (TNNI3K) on sepsis-induced myocardial dysfunction (SIMD) and further explore the underlying molecular mechanisms. In this study, a lipopolysaccharide- (LPS-) induced… read more here.

Keywords: apoptosis; related proteins; kinase; apoptosis related ... See more keywords
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Phenanthridone Alkaloids of the Amaryllidaceae as Activators of the Apoptosis-related Proteolytic Enzymes, Caspases

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Published in 2018 at "Natural Product Communications"

DOI: 10.1177/1934578x1801301035

Abstract: Apoptosis-inducing anticancer drugs have garnered widespread interest in recent years. Targets which concomitantly also exhibit minimal adverse effects in normal, healthy cells have been particularly well-received. The phenanthridone alkaloids such as pancratistatin and narciclasine exemplify… read more here.

Keywords: alkaloids amaryllidaceae; amaryllidaceae activators; apoptosis related; phenanthridone alkaloids ... See more keywords
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Quercetin modulates age-induced changes in the transcript levels of some apoptosis related genes in the skeletal muscles of male rats

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Published in 2020 at "Brazilian Journal of Pharmaceutical Sciences"

DOI: 10.1590/s2175-979020200003180861

Abstract: Adverse changes occur gradually in the skeletal muscles with age via continuous exposure to oxidative stress. Quercetin, a member of the flavonoids family, possesses anti-oxidative and radical-scavenging activities. Therefore, this study investigated the role of… read more here.

Keywords: age; skeletal muscles; apoptosis related; age induced ... See more keywords
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Identification and validation of a five apoptosis-related genes signature for prediction of disease-free survival for testicular germ cell tumors.

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Published in 2021 at "Translational andrology and urology"

DOI: 10.21037/tau-20-1247

Abstract: Background More and more studies have paid attention to the role of apoptosis in tumorigenesis. A variety of apoptosis-related genes (ARGs) are related to tumor progression and resistance to chemotherapy drugs. Therefore, this study aims… read more here.

Keywords: risk; apoptosis related; related genes; signature ... See more keywords
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Integrated analysis of immune- and apoptosis-related lncRNA-miRNA-mRNA regulatory network in children with Henoch Schönlein purpura nephritis

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Published in 2022 at "Translational Pediatrics"

DOI: 10.21037/tp-22-437

Abstract: Background Long noncoding RNAs (lncRNAs) play important roles in the regulation of immunological and apoptotic function. This study aimed to explore the critical immune- and apoptosis-related lncRNAs in the occurrence and development of Henoch-Schönlein purpura… read more here.

Keywords: mirna mrna; apoptosis; regulatory network; immune apoptosis ... See more keywords
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Apoptosis-related Proteins Are Altered by Selective Tyrosine Kinase Inhibitors and Everolimus in HPV-dependent SCC

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Published in 2020 at "AntiCancer Research"

DOI: 10.21873/anticanres.14639

Abstract: Background: Head and neck squamous cell cancer (HNSCC) affects the oral cavity and the pharynx. The aim of the study was to investigate the effects of selective tyrosine kinase inhibitors (TKIs) erlotinib, gefitinib, nilotinib and… read more here.

Keywords: kinase inhibitors; selective tyrosine; scc; apoptosis related ... See more keywords