MicroRNA-145 protects follicular granulosa cells against oxidative stress-induced apoptosis by targeting Krüppel-like factor 4
Sign Up to like & getrecommendations! Published in 2017 at "Molecular and Cellular Endocrinology"
DOI: 10.1016/j.mce.2017.05.030
Abstract: Oxidative stress-induced follicular granulosa cell (GC) apoptosis plays an essential role in abnormal follicular atresia, which may trigger ovarian dysfunction. To investigate the role of microRNA (miR)-145 in the regulation of GC apoptosis and modulation… read more here.
Keywords: mir 145; apoptosis; induced apoptosis; apoptosis targeting ... See more keywords
miR-181a promotes porcine granulosa cell apoptosis by targeting TGFBR1 via the activin signaling pathway
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DOI: 10.1016/j.mce.2019.110603
Abstract: Activin/Smad3 signaling plays a pivotal role in follicle development and atresia. However, the precise mechanisms underlying this process are not yet fully understood. Herein, we identified miR-181a as a central component of activin/Smad3-mediated follicle atresia.… read more here.
Keywords: activin; apoptosis; apoptosis targeting; porcine granulosa ... See more keywords
MicroRNA-433 regulates apoptosis by targeting PDCD4 in human osteosarcoma cells.
Sign Up to like & getrecommendations! Published in 2017 at "Oncology letters"
DOI: 10.3892/ol.2017.6441
Abstract: Osteosarcoma is the most common aggressive sarcoma of the bone in children and adolescents. It is characterized by a high level of genetic instability and recurrent DNA deletions and amplifications. microRNAs (miRNAs) play a key… read more here.
Keywords: microrna 433; mir 433; apoptosis targeting; osteosarcoma ... See more keywords