Cytotoxic and apoptotic activity of nitrofuroxans on lymphoma cells
Sign Up to like & getrecommendations! Published in 2018 at "Chemistry of Heterocyclic Compounds"
DOI: 10.1007/s10593-018-2232-z
Abstract: Five nitrofuroxans were synthesized and evaluated for their in vitro cytotoxicity against human lymphoma cells with different p53 status (Raji Burkitt's lymphoma and MOLT-4). The most promising compound exhibited IC50 values of 2.6–11.0 μM in… read more here.
Keywords: activity nitrofuroxans; microscopy; lymphoma cells; nitrofuroxans lymphoma ... See more keywords
Synthesis, spectroscopic analysis (FT-IR, UV and NMR) and DFT analysis of novel prodrugs of pregnane, their apoptotic activity in cervical cancer cell lines
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Molecular Structure"
DOI: 10.1016/j.molstruc.2018.04.009
Abstract: Abstract We report the synthesis and characterization of novel nitrogen containing pregnane-prodrugs 2 , 3 and 4 . The synthesized compounds were characterized with the help of modern spectroscopic techniques like 1 H, 13 C… read more here.
Keywords: dft; analysis; apoptotic activity; cervical cancer ... See more keywords
C-terminal 20 residues of ORF3 protein of duck circovirus genotype 2 regulates the nuclear localization and inhibits apoptotic activity of ORF3 protein.
Sign Up to like & getrecommendations! Published in 2018 at "Veterinary microbiology"
DOI: 10.1016/j.vetmic.2017.12.002
Abstract: Duck circovirus (DuCV) is divided into genotypes 1 and 2. The DuCV ORF3 protein is a newly identified viral protein with apoptotic activity. In this study, the differences in the gene sequences, subcellular localization, and… read more here.
Keywords: protein; nuclear localization; apoptotic activity; genotype ... See more keywords
Effect of Structural Changes Induced by Deletion of 54FLRAPSWF61 Sequence in αB-crystallin on Chaperone Function and Anti-Apoptotic Activity
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms221910771
Abstract: Previously, we showed that the removal of the 54–61 residues from αB-crystallin (αBΔ54–61) results in a fifty percent reduction in the oligomeric mass and a ten-fold increase in chaperone-like activity. In this study, we investigated… read more here.
Keywords: protein; anti apoptotic; apoptotic activity; deletion ... See more keywords
Apoptotic Activity of New Oxisterigmatocystin Derivatives from the Marine-Derived Fungus Aspergillus nomius NC06
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DOI: 10.3390/md19110631
Abstract: Sponge-derived fungi have recently attracted attention as an important source of interesting bioactive compounds. Aspergillus nomius NC06 was isolated from the marine sponge Neopetrosia chaliniformis. This fungus was cultured on rice medium and yielded four… read more here.
Keywords: aspergillus nomius; activity new; apoptotic activity; nomius nc06 ... See more keywords
Enhanced apoptotic activity in allergic diseases and its relationship with eosinophil cationic protein, systemic inflammation, and severity of atopic sensitisation
Sign Up to like & getrecommendations! Published in 2020 at "Archives of Medical Science"
DOI: 10.5114/aoms.2020.96346
Abstract: Introduction: The association between serum soluble apoptotic markers, eosinophil cationic protein (ECP), and inflammatory parameters in allergic diseases has seldom been studied. This study aimed to investigate apoptotic activity in allergic diseases and its relationship… read more here.
Keywords: allergic diseases; trail; apoptotic activity; severity atopic ... See more keywords