The synthesis, antifungal and apoptotic effects of triazole-oxadiazoles against Candida species.
Sign Up to like & getrecommendations! Published in 2018 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2017.12.020
Abstract: In search of potent and safe antifungal agents, herein, we report the synthesis, characterization and biological activities of triazole-oxadiazole compounds. The structural verification of the molecules was carried out by 1H NMR, 13C NMR and… read more here.
Keywords: synthesis antifungal; apoptotic effects; triazole oxadiazoles; thio ... See more keywords
Anti-apoptotic effects of human gingival mesenchymal stromal cells on polymorphonuclear leukocytes.
Sign Up to like & getrecommendations! Published in 2021 at "Oral diseases"
DOI: 10.1111/odi.13768
Abstract: OBJECTIVES Polymorphonuclear leukocytes (PMNs) constitute the first line of host defence and are crucial in maintaining periodontal health. Their survival and function are modulated by mesenchymal stromal cells (MSCs) from different origin. Gingival MSCs (GMSCs)… read more here.
Keywords: mesenchymal stromal; polymorphonuclear leukocytes; anti apoptotic; apoptotic effects ... See more keywords
Cytotoxic and Apoptotic Effects of Govaniadine Isolated from Corydalis govaniana Wall. Roots on Human Breast Cancer (MCF-7) Cells
Sign Up to like & getrecommendations! Published in 2018 at "BioMed Research International"
DOI: 10.1155/2018/3171348
Abstract: Current breast cancer therapies have limitations in terms of increased drug resistance resulting in short-term efficacy, thus demanding the discovery of new therapeutic agents. In this study, cytotoxic activity and apoptotic effects of govaniadine isolated… read more here.
Keywords: mcf; mcf cells; apoptotic effects; breast cancer ... See more keywords
Differential anti-proliferative and apoptotic effects of lichen species on human prostate carcinoma cells
Sign Up to like & getrecommendations! Published in 2020 at "PLoS ONE"
DOI: 10.1371/journal.pone.0238303
Abstract: Lichens are stable symbiotic associations between fungus and algae and/or cyanobacteria that have different biological activities. Around 60% of anti-cancer drugs are derived from natural resources including plants, fungi, sea creatures, and lichens. This project… read more here.
Keywords: anti proliferative; cell; apoptotic effects; proliferative apoptotic ... See more keywords
Enhanced Pro-apoptotic Effects of Fe(II)-Modified IVIG on Human Neutrophils
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2020.00973
Abstract: Mild modification of intravenous immunoglobulin (IVIG) has been reported to result in enhanced polyspecificity and leveraged therapeutic effects in animal models of inflammation. Here, we observed that IVIG modification by ferrous ions, heme or low… read more here.
Keywords: enhanced pro; apoptotic effects; pro apoptotic; effects modified ... See more keywords
Differential Apoptotic Effects of Bee Product Mixtures on Normal and Cancer Hepatic Cells
Sign Up to like & getrecommendations! Published in 2023 at "Antioxidants"
DOI: 10.3390/antiox12030615
Abstract: Most effective anticancer drugs normally generate considerable cytotoxicity in normal cells; therefore, the preferential activation of apoptosis in cancer cells and the reduction of toxicity in normal cells is a great challenge in cancer research.… read more here.
Keywords: honey; hepatic cells; apoptotic effects; normal cancer ... See more keywords
The Antiproliferative and Apoptotic Effects of a Novel Quinazoline Carrying Substituted-Sulfonamides: In Vitro and Molecular Docking Study
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27030981
Abstract: In order to investigate for a new effective and safe anticancer drug, we synthesized a novel series of quinazoline containing biologically active substituted-sulfonamide moiety at 3- position 4a–n. The structure of the newly prepared compounds… read more here.
Keywords: molecular docking; cell; novel quinazoline; apoptotic effects ... See more keywords
Antiproliferative and apoptotic effects of high-dose vitamin C in cholangiocarcinoma cell line
Sign Up to like & getrecommendations! Published in 2018 at "Tropical Journal of Pharmaceutical Research"
DOI: 10.4314/tjpr.v17i6.9
Abstract: Purpose : To evaluate the antiproliferative and apoptotic effects of high-dose vitamin C in cholangiocarcinoma cell line (CCA). Methods : Sulforhodamine B colorimetric assay was used to determine cell proliferation in human K100- CCA cell… read more here.
Keywords: effects high; apoptotic effects; ascorbic acid; vitamin cholangiocarcinoma ... See more keywords