Tannin-rich extracts from Lannea stuhlmannii and Lannea humilis (Anacardiaceae) exhibit hepatoprotective activities in vivo via enhancement of the anti-apoptotic protein Bcl-2
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DOI: 10.1038/s41598-018-27452-8
Abstract: The potential hepatoprotective activities of two Lannea species were explored in vivo. Furthermore, the binding activities of their main polyphenols to the antiapoptotic protein Bcl-2 were investigated. Based on HPLC-MS/MS results, 22 secondary metabolites were… read more here.
Keywords: protein bcl; hepatoprotective activities; apoptotic protein; anti apoptotic ... See more keywords
Plants expressing murine pro-apoptotic protein Bid do not have enhanced PCD
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DOI: 10.1186/s13104-020-05285-x
Abstract: Objectives The purpose of this study was to explore whether plant programmed cell death (PCD) cascade can sense the presence of the animal-only BH3 protein Bid, a BCL-2 family protein known to play a regulatory… read more here.
Keywords: protein; protein bid; pro apoptotic; apoptotic protein ... See more keywords
326-LB: BCL-xL/BCL2L1 Is a Critical Anti-Apoptotic Protein that Suppresses BAK to Promote Pancreatic Specification from Human Pluripotent Stem Cells
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DOI: 10.2337/db19-326-lb
Abstract: The differentiation of human pluripotent stem cells (hPSCs) into desired cell types such as the pancreatic cells involve cellular proliferation and apoptosis during cell fate transitions. Although different rates of cell growth and death are… read more here.
Keywords: anti apoptotic; none; pancreatic specification; bcl ... See more keywords