Polymer Nanoparticles Overcome Drug Resistance by a Dual-Targeting Apoptotic Signaling Pathway in Breast Cancer.
Sign Up to like & getrecommendations! Published in 2022 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.1c23146
Abstract: Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) activating therapy has received wide attention due to its capacity to precisely induce cancer cell apoptosis. However, drug resistance and the poor pharmacokinetic properties of TRAIL protein are obstacles… read more here.
Keywords: trail; apoptotic signaling; breast cancer; cancer ... See more keywords
A Dual-Responsive DNA Nanodevice for the Available Imaging of an Apoptotic Signaling Pathway In Situ.
Sign Up to like & getrecommendations! Published in 2019 at "ACS nano"
DOI: 10.1021/acsnano.9b05082
Abstract: Fluorescence imaging tools enable the in situ visualization of those molecules involved in various cell signaling pathways. But directly describing these pathways instead of the separate mediators in situ is much more meaningful and still… read more here.
Keywords: responsive dna; dna; dual responsive; apoptotic signaling ... See more keywords
Immunoediting role for major vault protein in apoptotic signaling induced by bacterial N-acyl homoserine lactones
Sign Up to like & getrecommendations! Published in 2021 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2012529118
Abstract: Significance It has become clear that our immune system can significantly inhibit the growth of cancer cells, in a process that has been coined “cancer immunoediting.” Based on this model, if the programmed cell death… read more here.
Keywords: cancer; apoptotic signaling; major vault; vault protein ... See more keywords
Detoxification of Mitochondrial Oxidants and Apoptotic Signaling Are Facilitated by Thioredoxin-2 and Peroxiredoxin-3 during Hyperoxic Injury
Sign Up to like & getrecommendations! Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0168777
Abstract: Mitochondria play a fundamental role in the regulation of cell death during accumulation of oxidants. High concentrations of atmospheric oxygen (hyperoxia), used clinically to treat tissue hypoxia in premature newborns, is known to elicit oxidative… read more here.
Keywords: accumulation; system; apoptotic signaling; thioredoxin ... See more keywords
HnRNP-L mediates bladder cancer progression by inhibiting apoptotic signaling and enhancing MAPK signaling pathways
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.14600
Abstract: Heterogeneous nuclear ribonucleoprotein L (hnRNP-L) is a promoter of various kinds of cancers, but its actions in bladder cancer (BC) are unclear. In this study, we investigated the function and the underlying mechanism of hnRNP-L… read more here.
Keywords: bladder cancer; hnrnp; apoptotic signaling; mapk signaling ... See more keywords