The Effects of Extracellular Serum Concentration on APP Processing in Npc1-Deficient APP-Overexpressing N2a Cells
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DOI: 10.1007/s12035-017-0799-5
Abstract: Amyloid precursor protein (APP) is cleaved by a set of proteases including α-/β-/γ- and recently identified η-secretases, generating C-terminal fragments (CTFs) of varying lengths and amyloid β (Aβ) peptides, which are considered to play a… read more here.
Keywords: app cleaved; app; cholesterol; serum concentration ... See more keywords