Role of human GKN1 on APP processing in gastric cancer.
Sign Up to like & getrecommendations! Published in 2017 at "Biochimie"
DOI: 10.1016/j.biochi.2017.02.007
Abstract: Gastrokine 1 (GKN1) is highly expressed in gastric tissue and is secreted into the stomach but is not expressed in gastric cancer. GKN1 belongs to the BRICHOS domain family and plays a major role in… read more here.
Keywords: app processing; gastric cancer; gkn1; human gkn1 ... See more keywords
Methamphetamine regulates βAPP processing in human neuroblastoma cells
Sign Up to like & getrecommendations! Published in 2019 at "Neuroscience Letters"
DOI: 10.1016/j.neulet.2019.02.023
Abstract: Methamphetamine is a potent and highly addictive psychostimulant whose abuse has turned out to be a global health hazard. The multitudinous effects it exerts at the cellular level induces neurotoxic responses in the human brain,… read more here.
Keywords: methamphetamine regulates; app processing; regulates app; human neuroblastoma ... See more keywords
The lipid raft-dwelling protein US9 can be manipulated to target APP compartmentalization, APP processing, and neurodegenerative disease pathogenesis
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-15128-8
Abstract: The trafficking behavior of the lipid raft-dwelling US9 protein from Herpes Simplex Virus strikingly overlaps with that of the amyloid precursor protein (APP). Both US9 and APP processing machinery rely on their ability to shuttle… read more here.
Keywords: protein; neurodegenerative disease; app processing; raft dwelling ... See more keywords
&bgr;APP Processing Drives Gradual Tau Pathology in an Age-Dependent Amyloid Rat Model of Alzheimer’s Disease
Sign Up to like & getrecommendations! Published in 2018 at "Cerebral Cortex"
DOI: 10.1093/cercor/bhx260
Abstract: The treatment of Alzheimer's disease (AD) remains challenging and requires a better in depth understanding of AD progression. Particularly, the link between amyloid protein precursor (APP) processing and Tau pathology development remains poorly understood. Growing… read more here.
Keywords: app processing; alzheimer disease; tau pathology; pathology ... See more keywords
Exercise training and BDNF injections alter APP processing enzymes and improve cognition.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of applied physiology"
DOI: 10.1152/japplphysiol.00114.2023
Abstract: Exercise reduces cognitive aging, neurodegeneration, and Alzheimer's disease (AD) risk. Acute exercise reduces the activity of beta-site amyloid precursor protein cleaving enzyme 1 (BACE1), the rate limiting enzyme in the production of Aβ. However, mechanisms… read more here.
Keywords: training bdnf; app processing; exercise training; bdnf ... See more keywords
NAP: Natural App Processing for Predictive User Contexts in Mobile Smartphones
Sign Up to like & getrecommendations! Published in 2020 at "Applied Sciences"
DOI: 10.3390/app10196657
Abstract: The resource management of an application is an essential task in smartphones. Optimizing the application launch process results in a faster and more efficient system, directly impacting the user experience. Predicting the next application that… read more here.
Keywords: application; app processing; natural app; processing predictive ... See more keywords