Articles with "app21 transgenic" as a keyword



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APP21 transgenic rats develop age-dependent cognitive impairment and microglia accumulation within white matter tracts

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Published in 2018 at "Journal of Neuroinflammation"

DOI: 10.1186/s12974-018-1273-7

Abstract: BackgroundMost of the animal models commonly used for preclinical research into Alzheimer’s disease (AD) largely fail to address the pathophysiology, including the impact of known risk factors, of the widely diagnosed sporadic form of the… read more here.

Keywords: transgenic rats; age; pathology; app21 transgenic ... See more keywords