Efficacy of Systemic Chemotherapy in Patients With Low-grade Mucinous Appendiceal Adenocarcinoma
Sign Up to like & getrecommendations! Published in 2023 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2023.16161
Abstract: Key Points Question Is fluoropyrimidine-based systemic chemotherapy effective in treating patients with inoperable low-grade mucinous appendiceal adenocarcinoma? Findings In this randomized crossover trial that included 24 patients, there was no significant difference in tumor growth… read more here.
Keywords: grade mucinous; appendiceal adenocarcinoma; mucinous appendiceal; low grade ... See more keywords
Predictors of lymph node metastases in patients with mucinous appendiceal adenocarcinoma
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DOI: 10.1002/jso.25963
Abstract: Lymph node metastasis (LN+) is a prognostic factor in appendiceal cancers, but predictors and outcomes for LN+ in mucinous appendiceal adenocarcinoma (MAC) remain poorly defined. read more here.
Keywords: predictors lymph; node metastases; appendiceal adenocarcinoma; lymph node ... See more keywords
National trends in the presentation of surgically resected appendiceal adenocarcinoma over a decade
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DOI: 10.1002/jso.26295
Abstract: Rates of nonoperative management of acute appendicitis and appendiceal adenocarcinoma have increased over a decade, but the presentation and outcomes of appendiceal adenocarcinoma over this period is not well‐characterized. read more here.
Keywords: trends presentation; appendiceal adenocarcinoma; national trends; decade ... See more keywords
Cancer embryonic antigen (CEA) levels in patients with appendiceal adenocarcinoma predict response to neo‐adjuvant chemotherapy and overall survival
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Surgical Oncology"
DOI: 10.1002/jso.27178
Abstract: Serum tumor markers are widely used for diagnosis, prognosis, treatment response, and surveillance. Our study evaluated cancer embryonic antigen (CEA) in patients with appendiceal adenocarcinoma. read more here.
Keywords: antigen cea; appendiceal adenocarcinoma; cancer embryonic; response ... See more keywords
The Role of Adjuvant Chemotherapy Following Right Hemicolectomy for Non-metastatic Mucinous and Nonmucinous Appendiceal Adenocarcinoma
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Gastrointestinal Surgery"
DOI: 10.1007/s11605-021-05076-0
Abstract: Appendiceal adenocarcinoma (AA) represents a heterogenous group of neoplasms with distinct histologic features. The role and efficacy of adjuvant chemotherapy (AC) in non-metastatic disease remain controversial. The aim of this study was to ascertain the… read more here.
Keywords: stage iii; appendiceal adenocarcinoma; role; stage ... See more keywords
Lymph Node Positivity in Appendiceal Adenocarcinoma: Should Size Matter?
Sign Up to like & getrecommendations! Published in 2017 at "Journal of the American College of Surgeons"
DOI: 10.1016/j.jamcollsurg.2017.01.056
Abstract: BACKGROUND The management algorithm for appendiceal adenocarcinoma is not well defined. This study sought to determine whether tumor size or depth of invasion better correlates with the presence of lymph node metastases in appendiceal adenocarcinoma,… read more here.
Keywords: appendiceal adenocarcinoma; size; lymph node; node metastases ... See more keywords
Appendectomy is Oncologically Equivalent to Right Hemicolectomy for Well Differentiated T1 Appendiceal Adenocarcinoma.
Sign Up to like & getrecommendations! Published in 2021 at "Diseases of the colon and rectum"
DOI: 10.1097/dcr.0000000000002089
Abstract: BACKGROUND Right hemicolectomy is recommended for appendiceal adenocarcinoma but may not be needed for early-stage disease. OBJECTIVE This study aimed to determine whether appendectomy offers adequate oncologic outcomes for T1 appendiceal adenocarcinoma from a national… read more here.
Keywords: well differentiated; appendiceal adenocarcinoma; right hemicolectomy; disease ... See more keywords
Appendiceal adenocarcinoma is associated with better prognosis than cecal adenocarcinoma: a population-based comparative survival study
Sign Up to like & getrecommendations! Published in 2023 at "BMJ Open Gastroenterology"
DOI: 10.1136/bmjgast-2022-001045
Abstract: Objective Although appendiceal cancer remains a rare gastrointestinal malignancy compared with colorectal cancer, incidence rates of appendiceal cancer have increased in the last two decades. Appendiceal and cecal adenocarcinomas have distinct genomic profiles, but chemotherapy… read more here.
Keywords: appendiceal adenocarcinoma; survival; comparative survival; adenocarcinoma ... See more keywords
Targeting GNAS mutant appendiceal adenocarcinoma.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2021.39.3_suppl.470
Abstract: 470Background: Appendiceal cancers are rare, comprising just 0.5% of all intestinal neoplasia, preventing the systematic study of these tumors in randomized clinical trials. Given this absence of c... read more here.
Keywords: mutant appendiceal; targeting gnas; appendiceal adenocarcinoma; oncology ... See more keywords
Organoids From Mucinous Appendiceal Adenocarcinomas as High-Fidelity Models for Individual Therapy
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Medicine"
DOI: 10.3389/fmed.2022.829033
Abstract: Background Mucinous appendiceal adenocarcinoma (MAA) is a rare, heterogeneous disease. Patients with unrespectable mucinous appendiceal adenocarcinoma presenting with peritoneal spread are treated by intraperitoneal chemotherapy, hyperthermic intraperitoneal chemotherapy, systemic chemotherapy, or targeted therapy. However, there… read more here.
Keywords: appendiceal adenocarcinoma; ic50; therapy; mucinous appendiceal ... See more keywords