Fracture rate and time to fracture in dogs with appendicular osteosarcoma receiving finely fractionated compared to coarsely fractionated radiation therapy: A single institution study
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DOI: 10.1002/vms3.782
Abstract: Abstract Background Radiation therapy (RT) is used for local pain alleviation in dogs with appendicular osteosarcoma (OS), especially among dogs that are poor surgical candidates for amputation. However, many historical reports of fractionated protocols lack… read more here.
Keywords: time fracture; fracture; appendicular osteosarcoma; fracture rate ... See more keywords
Prevalence and potentially prognostic value of C‐circles associated with alternative lengthening of telomeres in canine appendicular osteosarcoma
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DOI: 10.1111/vco.12665
Abstract: Abstract Alternative lengthening of telomeres (ALT) is a telomerase‐independent telomere maintenance mechanism (TMM) with high prevalence in human osteosarcomas but remains unknown in canine osteosarcomas. The aim of this study was to evaluate the prevalence… read more here.
Keywords: alternative lengthening; prevalence; appendicular osteosarcoma; osteosarcomas ... See more keywords
Staging canine patients with appendicular osteosarcoma utilizing fluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography compared to whole body computed tomography.
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DOI: 10.1111/vco.12805
Abstract: Few studies have investigated the diagnostic performance of fluorine-18-fluorodeoxyglucose (18 F-FDG) positron emission tomography/computed tomography (PET/CT) for staging veterinary patients with appendicular osteosarcoma. The purpose of this study was to evaluate the efficacy of 18… read more here.
Keywords: whole body; computed tomography; tomography; fdg pet ... See more keywords
Pain characterization and response to palliative care in dogs with naturally-occurring appendicular osteosarcoma: An open label clinical trial
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DOI: 10.1371/journal.pone.0207200
Abstract: This study aimed to characterize bone cancer pain (quantitative sensory testing (QST), stance asymmetry index, actimetry, scores of pain and quality of life (QoL)) in dogs with appendicular osteosarcoma (OSA), and to evaluate a stepwise… read more here.
Keywords: treatment; actimetry; label clinical; appendicular osteosarcoma ... See more keywords
Unraveling the chaotic genomic landscape of primary and metastatic canine appendicular osteosarcoma with current sequencing technologies and bioinformatic approaches.
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DOI: 10.1371/journal.pone.0246443
Abstract: Osteosarcoma is a rare disease in children but is one of the most common cancers in adult large breed dogs. The mutational landscape of both the primary and pulmonary metastatic tumor in two dogs with… read more here.
Keywords: canine; osteosarcoma; landscape primary; landscape ... See more keywords
Three hematological indexes that may serve as prognostic indicators in patients with primary, high-grade, appendicular osteosarcoma
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DOI: 10.18632/oncotarget.17811
Abstract: Background Although alkaline phosphatase (ALP) and lactate dehydrogenase (LDH) are considered effective prognostic factors of osteosarcoma, useful prognostic biomarkers for patients with osteosarcoma are still lacking. Methods A retrospective study of 106 patients with primary,… read more here.
Keywords: grade appendicular; high grade; appendicular osteosarcoma; primary high ... See more keywords
Comparative Evaluation of Nutraceuticals (Curcuma longa L., Syzygium aromaticum L. and Olea europaea) with Single-agent Carboplatin in the Management of Canine Appendicular Osteosarcoma
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DOI: 10.18805/ijar.b-4485
Abstract: Background: Canine appendicular osteosarcoma (OSA) is the most common bone malignancy in dogs. Methods: Spontaneous cases of canine OSA presented for three years were treated with different standard therapeutic protocols and compared with a novel plant… read more here.
Keywords: canine appendicular; canine; carboplatin; appendicular osteosarcoma ... See more keywords
Retrospective Evaluation of Outcome in Dogs With Appendicular Osteosarcoma Following Hypofractionated Palliative Radiation Therapy With or Without Bisphosphonates: 165 Cases (2010–2019)
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Veterinary Science"
DOI: 10.3389/fvets.2022.892297
Abstract: Objective To report the survival times in dogs that received a standardized palliative-intent radiation therapy (RT) protocol for the treatment of canine appendicular osteosarcoma (OSA), alone or in combination with bisphosphonates (BPs), and to determine… read more here.
Keywords: outcome dogs; radiation therapy; 2010 2019; treatment ... See more keywords