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WNT Inhibitory Activity of Malus Pumila miller cv Annurca and Malus domestica cv Limoncella Apple Extracts on Human Colon-Rectal Cells Carrying Familial Adenomatous Polyposis Mutations

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Published in 2017 at "Nutrients"

DOI: 10.3390/nu9111262

Abstract: Inhibitors of the Wingless-related Integration site (WNT)/β-catenin pathway have recently been under consideration as potential chemopreventive agents against Familial Adenomatous Polyposis (FAP). This autosomal-dominant syndrome is caused by germline mutations in the gene coding for… read more here.

Keywords: wnt inhibitory; apple extracts; cells carrying; inhibitory activity ... See more keywords