Articles with "application nudt15" as a keyword



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Pharmacogenetics of thiopurines for inflammatory bowel disease in East Asia: prospects for clinical application of NUDT15 genotyping

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Published in 2017 at "Journal of Gastroenterology"

DOI: 10.1007/s00535-017-1416-0

Abstract: The thiopurine drugs 6-mercaptopurine (6-MP) and azathiopurine (AZA) are widely used to treat inflammatory bowel disease. However, the incidence of adverse reactions is high, particularly in Asia, and the mechanisms of toxicity in Asian populations… read more here.

Keywords: application nudt15; bowel disease; inflammatory bowel; asian populations ... See more keywords