Determination of an isonicotinylhydrazide derivative, a novel positive inotropic compound, in mouse plasma by LC–MS/MS and its application to a pharmacokinetics study
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DOI: 10.1016/j.jpba.2018.10.034
Abstract: HighlightsA simple, rapid and efficient pretreatment of AF‐HF001 is reported.A full validated LC–MS/MS method of AF‐HF001 is described for the first time.Successful application to a pharmacokinetics study of AF‐HF001 in mice plasma.First mice pharmacokinetics report… read more here.
Keywords: application pharmacokinetics; isonicotinylhydrazide derivative; positive inotropic; hf001 ... See more keywords