An umpolung reaction of α-iminonitriles and its application to the synthesis of aminomalononitriles
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DOI: 10.1039/c9nj05114g
Abstract: An umpolung N-alkylation reaction of α-iminonitriles with Grignard reagents affords the corresponding N-alkylated α-aminonitriles in good yields. Subsequent oxidation and cyanation of the N-alkylated products proceeds effectively to give aminomalononitriles in good yields, and the… read more here.
Keywords: iminonitriles application; umpolung reaction; application synthesis; reaction ... See more keywords
Electrophilic Metal Homoenolates and Their Application in the Synthesis of Cyclopropylamines
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DOI: 10.1055/s-0036-1591536
Abstract: Since their discovery, metal homoenolates have been widely explored as carbon-based nucleophiles for the β-functionalization of carbonyl derivatives. Only recently has it been reported that metal homoenolates can react as carbonyl electrophiles. In this context,… read more here.
Keywords: electrophilic metal; metal; application synthesis; homoenolates application ... See more keywords