Applications of CRISPR/Cas9 technology for modification of the plant genome
Sign Up to like & getrecommendations! Published in 2022 at "Genetica"
DOI: 10.1007/s10709-021-00146-2
Abstract: The CRISPR/Cas (Clustered regularly interspaced short palindromic repeats/ CRISPR associated protein 9) system was discovered in bacteria and archea as an acquired immune response to protect the cells from infection. This technology has now evolved… read more here.
Keywords: plant genome; applications crispr; crispr cas9; technology ... See more keywords
Disruptive non-disruptive applications of CRISPR/Cas9.
Sign Up to like & getrecommendations! Published in 2017 at "Current opinion in biotechnology"
DOI: 10.1016/j.copbio.2017.06.001
Abstract: The bacterial type II Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-CRISPR Associated (Cas) systems, and in particular Streptococcus pyogenes CRISPR-Cas9, have been broadly applied to edit the genome of bacterial and eukaryotic cells. Cas9, which… read more here.
Keywords: disruptive applications; crispr cas9; non disruptive; applications crispr ... See more keywords
Methods and Applications of CRISPR-Mediated Base Editing in Eukaryotic Genomes.
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DOI: 10.1016/j.molcel.2017.09.029
Abstract: The past several years have seen an explosion in development of applications for the CRISPR-Cas9 system, from efficient genome editing, to high-throughput screening, to recruitment of a range of DNA and chromatin-modifying enzymes. While homology-directed… read more here.
Keywords: base editing; mediated base; methods applications; crispr mediated ... See more keywords
Applications of CRISPR genome editing technology in drug target identification and validation
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DOI: 10.1080/17460441.2017.1317244
Abstract: ABSTRACT Introduction: The analysis of pharmaceutical industry data indicates that the major reason for drug candidates failing in late stage clinical development is lack of efficacy, with a high proportion of these due to erroneous… read more here.
Keywords: genome editing; target; drug; editing technology ... See more keywords
Therapeutic applications of CRISPR RNA-guided genome editing.
Sign Up to like & getrecommendations! Published in 2017 at "Briefings in functional genomics"
DOI: 10.1093/bfgp/elw032
Abstract: The rapid development of programmable nuclease-based genome editing technologies has enabled targeted gene disruption and correction both in vitro and in vivo This revolution opens up the possibility of precise genome editing at target genomic… read more here.
Keywords: genome editing; crispr rna; therapeutic applications; rna guided ... See more keywords
Applications of CRISPR/Cas9 in Reproductive Biology.
Sign Up to like & getrecommendations! Published in 2018 at "Current issues in molecular biology"
DOI: 10.21775/cimb.026.093
Abstract: Genome editing is unraveling its benefits in wide areas of scientific development and understanding. The advances of genome editing from ZFNs and TALLENs to CRISPRs defines it wide applicability. Reproduction is the fundamental process by… read more here.
Keywords: genome editing; crispr cas9; biology applications; biology ... See more keywords
Editorial: Methods and applications of CRISPR technology in plant sciences, 2022
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Plant Science"
DOI: 10.3389/fpls.2023.1207257
Abstract: The Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/Cas-mediated gene editing is a rapidly developing technique to investigate fundamental questions in Plant Science research and genetic improvement of plants. This system has been shown to work… read more here.
Keywords: editorial methods; applications crispr; crispr technology; methods applications ... See more keywords
Applications of CRISPR/Cas System to Bacterial Metabolic Engineering
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms19041089
Abstract: The clustered regularly interspaced short palindromic repeats/CRISPR-associated (CRISPR/Cas) adaptive immune system has been extensively used for gene editing, including gene deletion, insertion, and replacement in bacterial and eukaryotic cells owing to its simple, rapid, and… read more here.
Keywords: system bacterial; crispr cas; cas; cas system ... See more keywords
Applications of CRISPR-Cas9 in Alzheimer’s Disease and Related Disorders
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DOI: 10.3390/ijms23158714
Abstract: Alzheimer’s disease, Parkinson’s disease, amyotrophic lateral sclerosis, and Huntington’s disease represent some of the most prevalent neurodegenerative disorders afflicting millions of people worldwide. Unfortunately, there is a lack of efficacious treatments to cure or stop… read more here.
Keywords: crispr cas9; disease related; applications crispr; disease ... See more keywords