Articles with "applications isosteres" as a keyword



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Applications of Isosteres of Piperazine in the Design of Biologically Active Compounds: Part 1.

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Published in 2022 at "Journal of agricultural and food chemistry"

DOI: 10.1021/acs.jafc.2c00726

Abstract: Piperazine and homopiperazine are well-studied heterocycles in drug design that have found gainful application as scaffolds and terminal elements and for enhancing the aqueous solubility of a molecule. The optimization of drug candidates that incorporate… read more here.

Keywords: design; isosteres piperazine; applications isosteres; piperazine design ... See more keywords
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Applications of Isosteres of Piperazine in the Design of Biologically Active Compounds: Part 2.

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recommendations!
Published in 2022 at "Journal of agricultural and food chemistry"

DOI: 10.1021/acs.jafc.2c00729

Abstract: Applications of piperazine and homopiperazine in drug design are well-established, and these heterocycles have found use as both scaffolding and terminal elements and also as a means of introducing a water-solubilizing element into a molecule.… read more here.

Keywords: design; isosteres piperazine; applications isosteres; piperazine design ... See more keywords