Applications of proteomic methods for CHO host cell protein characterization in biopharmaceutical manufacturing.
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DOI: 10.1016/j.copbio.2018.01.004
Abstract: Chinese hamster ovary (CHO) cells are the most prevalent host organism for production of recombinant therapeutic proteins, including monoclonal antibodies (mAbs). Regulatory guidance mandates control of the host cell protein (HCP) concentration in the production… read more here.
Keywords: applications proteomic; host cell; cell protein; host ... See more keywords