Applied stretch initiates directional invasion through the action of Rap1 GTPase as a tension sensor
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DOI: 10.1242/jcs.180612
Abstract: ABSTRACT Although it is known that a stiffening of the stroma and the rearrangement of collagen fibers within the extracellular matrix facilitate the movement of tumor cells away from the primary lesion, the underlying mechanisms… read more here.
Keywords: invasion; tumor cells; applied stretch; rap1 ... See more keywords