Inactivation of Nitric Oxide Synthesis Exacerbates the Development of Alzheimer Disease Pathology in APPPS1 Mice (Amyloid Precursor Protein/Presenilin-1)
Sign Up to like & getrecommendations! Published in 2017 at "Hypertension"
DOI: 10.1161/hypertensionaha.117.09742
Abstract: The epidemiological link between hypertension and Alzheimer disease is established. We previously reported that hypertension aggravates the Alzheimer-like pathology in APPPS1 mice (amyloid precursor protein/presenilin-1, mouse model of Alzheimer disease) with angiotensin II–induced hypertension, in… read more here.
Keywords: alzheimer disease; pathology; appps1 mice; hypertension ... See more keywords
Seizing the Alzheimer’s Brain: A Role for Sirtuin 3 in Hyperexcitability
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DOI: 10.1177/1535759720932157
Abstract: SIRT3 Haploinsufficiency Aggravates Loss of GABAergic Interneurons and Neuronal Network Hyperexcitability in an Alzheimer’s Disease Model 1 Cheng A, Wang J, Ghena N, Zhao Q, Perone I, King TM, Veech RL, Gorospe M, Wan R,… read more here.
Keywords: hyperexcitability; appps1 mice; sirt3; neuronal network ... See more keywords