An Extended Approach for the Development of Fluorogenic trans‐Cyclooctene–Tetrazine Cycloadditions
Sign Up to like & getrecommendations! Published in 2019 at "Chembiochem"
DOI: 10.1002/cbic.201800711
Abstract: Inverse‐electron‐demand Diels–Alder (iEDDA) cycloaddition between 1,2,4,5‐tetrazines and strained dienophiles belongs among the most popular bioconjugation reactions. In addition to its fast kinetics, this cycloaddition can be tailored to produce fluorescent products from non‐fluorescent starting materials.… read more here.
Keywords: cycloaddition; extended approach; iedda cycloaddition; trans cyclooctene ... See more keywords
An innovative approach to development of new pyrazolylquinolin-2-one hybrids as dual EGFR and BRAFV600E inhibitors
Sign Up to like & getrecommendations! Published in 2025 at "Molecular Diversity"
DOI: 10.1007/s11030-025-11127-4
Abstract: Novel quinoline-based derivatives 2a–e and 4a–j have been designed and synthesized as potential antiproliferative agents. The designed compounds were screened for their antiproliferative activity against sixty cell lines according to NCI protocol. The promising hybrids… read more here.
Keywords: approach development; brafv600e; egfr brafv600e; development new ... See more keywords
A facile approach for the development of high mechanical strength 3D neuronal network scaffold based on chitosan and graphite nanoplatelets.
Sign Up to like & getrecommendations! Published in 2021 at "Carbohydrate polymers"
DOI: 10.1016/j.carbpol.2021.118420
Abstract: In this work, novel composite microparticles based on chitosan (CHI) and graphite nanoplatelets (GNP) were developed as 3D scaffolds for neuronal cells. The aim is to improve the scaffold strength while maintaining its ability to… read more here.
Keywords: strength; graphite nanoplatelets; based chitosan; facile approach ... See more keywords
Novel approach for the development of tailored heterogenous structures in steel
Sign Up to like & getrecommendations! Published in 2020 at "Materialia"
DOI: 10.1016/j.mtla.2020.100831
Abstract: Abstract A new strategy is introduced for developing architectured structures in medium carbon steels. The steel is initially decarburized within the austenitic range and quenched to produce a compositionally graded material with 0.4 wt% carbon at… read more here.
Keywords: novel approach; tailored heterogenous; approach development; steel ... See more keywords
Environmental Friendly Approach for the Development of Ultra-Low-Firing Li2WO4 Ceramic Tapes
Sign Up to like & getrecommendations! Published in 2018 at "ACS Sustainable Chemistry & Engineering"
DOI: 10.1021/acssuschemeng.8b00656
Abstract: Ultra-low-temperature co-fireable Li2WO4 substrate has been developed using an environmental friendly tape-casting technique. The nonaqueous tape-casting slurry comprised of an eco-friendly binder-solvent system consisting of polypropylene carbonate as binder and dimethyl carbonate as solvent. The… read more here.
Keywords: development ultra; ultra low; environmental friendly; approach development ... See more keywords
A big data approach to the development of mixed‐effects models for seizure count data
Sign Up to like & getrecommendations! Published in 2017 at "Epilepsia"
DOI: 10.1111/epi.13727
Abstract: Our objective was to develop a generalized linear mixed model for predicting seizure count that is useful in the design and analysis of clinical trials. This model also may benefit the design and interpretation of… read more here.
Keywords: big data; seizure count; model; approach development ... See more keywords
Sustainable Approach to Development of Antimicrobial Textile Pads for Sweat Absorption
Sign Up to like & getrecommendations! Published in 2024 at "Fibers"
DOI: 10.3390/fib12030020
Abstract: Double-layered textile sweat-absorbing underarm pads with a natural antimicrobial treatment can be used to solve the problem of the wetness sensation in the case of increased physical activity or hyperhidrosis. In addition, changeable antimicrobial active… read more here.
Keywords: approach development; underarm pads; textile; absorption ... See more keywords
A New Approach for the Development and Optimization of Gluten-Free Noodles Using Flours from Byproducts of Cold-Pressed Okra and Pumpkin Seeds
Sign Up to like & getrecommendations! Published in 2023 at "Foods"
DOI: 10.3390/foods12102018
Abstract: The significant protein and dietary fiber content of cold-pressed pumpkin (PSF) and okra (OSF) seed byproducts are well-known. However, their impact on noodles’ nutritional quality has never been studied. For the first time, noodle formulation… read more here.
Keywords: new approach; optimization gluten; approach development; development optimization ... See more keywords
Taking a Breath: A Systematic Approach to the Development of an Altered Airway eLearning Module by Unit Council Nurses.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of continuing education in nursing"
DOI: 10.3928/00220124-20230310-04
Abstract: After a needs assessment for care of patients with altered airways was performed, gaps in educational materials were identified and hospital learning management system educational resources were created/updated. Frontline nurses and clinical and administrative leaders… read more here.
Keywords: taking breath; development altered; approach development; development ... See more keywords