Practical asymmetric amine nucleophilic approach for the modular construction of protected α-quaternary amino acids
Sign Up to like & getrecommendations! Published in 2022 at "Chemical Science"
DOI: 10.1039/d2sc02318k
Abstract: We report the first amine nucleophilic approach for the modular construction of enantioenriched protected α-quaternary amino acids. The key to success is the use of an alcohol solvent, which makes a rationally designed COOMe-bonded Cu-allenylidene… read more here.
Keywords: amino acids; nucleophilic approach; amine nucleophilic; approach modular ... See more keywords
A bioarchitectonic approach to the modular engineering of metabolism
Sign Up to like & getrecommendations! Published in 2017 at "Philosophical Transactions of the Royal Society B: Biological Sciences"
DOI: 10.1098/rstb.2016.0387
Abstract: Dissociating the complexity of metabolic processes into modules is a shift in focus from the single gene/gene product to functional and evolutionary units spanning the scale of biological organization. When viewing the levels of biological… read more here.
Keywords: engineering; modular engineering; metabolism; bioarchitectonic approach ... See more keywords