Technical approaches and challenges to study AMPA receptors in oligodendrocyte lineage cells: Past, present, and future
Sign Up to like & getrecommendations! Published in 2022 at "Glia"
DOI: 10.1002/glia.24305
Abstract: Receptors for α‐amino‐3‐hydroxy‐5‐methyl‐4‐isoxazolepropionic acid (AMPARs) are ligand‐gated ionotropic receptors for glutamate that is a major excitatory neurotransmitter in the central nervous system. AMPARs are located at postsynaptic sites of neuronal synapses where they mediate fast… read more here.
Keywords: oligodendrocyte lineage; technical approaches; lineage cells; lineage ... See more keywords
Recent advances, approaches and challenges in targeting pathways for potential COVID-19 vaccines development
Sign Up to like & getrecommendations! Published in 2020 at "Immunologic Research"
DOI: 10.1007/s12026-020-09154-4
Abstract: During the COVID-19 pandemic in a modern era, there is a global consensus on the need for the rapid development of a vaccine against SARS-CoV-2 for effective and sustainable control. Developing these vaccines is fundamental… read more here.
Keywords: advances approaches; covid; challenges targeting; recent advances ... See more keywords
Macromolecule nanotherapeutics: approaches and challenges.
Sign Up to like & getrecommendations! Published in 2018 at "Drug discovery today"
DOI: 10.1016/j.drudis.2018.01.017
Abstract: With the advent of technology, newer forms of drugs, such as proteins, DNA, and RNA, have entered mainstream product development. However, systemic delivery of macromolecules is limited by rapid blood clearance, poor stability in vivo,… read more here.
Keywords: delivery; approaches challenges; macromolecule nanotherapeutics; nanotherapeutics approaches ... See more keywords
Corrigendum: New approaches and challenges to targeting the endocannabinoid system
Sign Up to like & getrecommendations! Published in 2018 at "Nature Reviews Drug Discovery"
DOI: 10.1038/nrd.2018.155
Abstract: This corrects the article DOI: 10.1038/nrd.2018.115 read more here.
Keywords: new approaches; endocannabinoid system; corrigendum new; challenges targeting ... See more keywords
Approaches and challenges in the synthesis of three-dimensional covalent-organic frameworks
Sign Up to like & getrecommendations! Published in 2018 at "Communications Chemistry"
DOI: 10.1038/s42004-018-0098-8
Abstract: Covalent organic frameworks, cross-linked crystalline polymers constructed from rigid organic precursors connected by covalent interactions, have emerged as a promising class of nanoporous materials owing to their highly desirable combination of attributes, including facile chemical… read more here.
Keywords: three dimensional; dimensional covalent; organic frameworks; approaches challenges ... See more keywords
The Human Cell Atlas: Technical approaches and challenges
Sign Up to like & getrecommendations! Published in 2018 at "Briefings in Functional Genomics"
DOI: 10.1093/bfgp/elx029
Abstract: Abstract The Human Cell Atlas is a large, international consortium that aims to identify and describe every cell type in the human body. The comprehensive cellular maps that arise from this ambitious effort have the… read more here.
Keywords: cell atlas; technical approaches; human cell; atlas technical ... See more keywords
Guided crowd evacuation: approaches and challenges
Sign Up to like & getrecommendations! Published in 2019 at "IEEE/CAA Journal of Automatica Sinica"
DOI: 10.1109/jas.2019.1911672
Abstract: Evacuation leaders and/ or equipment provide route and exit information for people and guide them to the expected destinations, which could make crowd evacuation more efficient in case of emergency. The purpose of this paper… read more here.
Keywords: approaches challenges; evacuation approaches; crowd evacuation; guided crowd ... See more keywords
3D and 4D Bioprinting of the Myocardium: Current Approaches, Challenges, and Future Prospects
Sign Up to like & getrecommendations! Published in 2018 at "BioMed Research International"
DOI: 10.1155/2018/6497242
Abstract: 3D and 4D bioprinting of the heart are exciting notions in the modern era. However, myocardial bioprinting has proven to be challenging. This review outlines the methods, materials, cell types, issues, challenges, and future prospects… read more here.
Keywords: future prospects; challenges future; myocardium current; approaches challenges ... See more keywords
Novel Approaches and Challenges of Discovery of Exosite Modulators of a Disintegrin and Metalloprotease 10
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2020.00075
Abstract: A disintegrin and metaproteinase 10 is an important target for multiple therapeutic areas, however, despite drug discovery efforts by both industry and academia no compounds have reached the clinic so far. The lack of enzyme… read more here.
Keywords: novel approaches; challenges discovery; approaches challenges; discovery exosite ... See more keywords
Approaches and Challenges for Biosensors for Acute and Chronic Heart Failure
Sign Up to like & getrecommendations! Published in 2023 at "Biosensors"
DOI: 10.3390/bios13020282
Abstract: Heart failure (HF) is a cardiovascular disease defined by several symptoms that occur when the heart cannot supply the blood needed by the tissues. HF, which affects approximately 64 million people worldwide and whose incidence… read more here.
Keywords: heart failure; challenges biosensors; acute chronic; heart ... See more keywords
Approaches and Challenges in Internet of Robotic Things
Sign Up to like & getrecommendations! Published in 2022 at "Future Internet"
DOI: 10.3390/fi14090265
Abstract: The Internet of robotic things (IoRT) is the combination of different technologies including cloud computing, robots, Internet of things (IoT), artificial intelligence (AI), and machine learning (ML). IoRT plays a major role in manufacturing, healthcare,… read more here.
Keywords: iort; internet robotic; security; challenges internet ... See more keywords