Luciferase Complementation Approaches to Measure GPCR Signaling Kinetics and Bias.
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DOI: 10.1007/978-1-0716-1221-7_17
Abstract: An understanding of the kinetic contributions to G protein-coupled receptor pharmacology and signaling is increasingly important in compound profiling. Nonequilibrium conditions are commonly present in vivo, for example, as the drug competes with dynamic changes… read more here.
Keywords: complementation approaches; approaches measure; gpcr signaling; pharmacology ... See more keywords