Bioinformatics Approaches to Predict Drug Responses from Genomic Sequencing.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7493-1_14
Abstract: Fulfilling the promises of precision medicine will depend on our ability to create patient-specific treatment regimens. Therefore, being able to translate genomic sequencing into predicting how a patient will respond to a given drug is… read more here.
Keywords: genomic sequencing; sequencing data; bioinformatics approaches; approaches predict ... See more keywords
In Silico Approaches to Predict Drug-Transporter Interaction Profiles: Data Mining, Model Generation, and Link to Cholestasis.
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DOI: 10.1007/978-1-4939-9420-5_26
Abstract: Transport proteins play a crucial role in drug distribution, disposition, and clearance by mediating cellular drug influx and efflux. Inhibition of these transporters may lead to drug-drug interactions or even drug-induced liver injury, such as… read more here.
Keywords: predict drug; approaches predict; drug; silico approaches ... See more keywords
Advanced EEG-based learning approaches to predict schizophrenia: Promises and pitfalls
Sign Up to like & getrecommendations! Published in 2021 at "Artificial intelligence in medicine"
DOI: 10.1016/j.artmed.2021.102039
Abstract: The complexity and heterogeneity of schizophrenia symptoms challenge an objective diagnosis, which is typically based on behavioral and clinical manifestations. Moreover, the boundaries of schizophrenia are not precisely demarcated from other nosologic categories, such as… read more here.
Keywords: schizophrenia; based learning; approaches predict; eeg based ... See more keywords
Anti-Drug Antibodies: Emerging Approaches to Predict, Reduce or Reverse Biotherapeutic Immunogenicity
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DOI: 10.3390/antib7020019
Abstract: The development of anti-drug antibodies (ADAs) following administration of biotherapeutics to patients is a vexing problem that is attracting increasing attention from pharmaceutical and biotechnology companies. This serious clinical problem is also spawning creative research… read more here.
Keywords: immunogenicity; approaches predict; drug antibodies; anti drug ... See more keywords