Genomic and Targeted Approaches Unveil the Cell Membrane as a Major Target of the Antifungal Cytotoxin Amantelide A
Sign Up to like & getrecommendations! Published in 2021 at "ChemBioChem"
DOI: 10.1002/cbic.202000685
Abstract: Amantelide A, a polyhydroxylated macrolide isolated from a marine cyanobacterium, displays broadâspectrum activity against mammalian cells, bacterial pathogens, and marine fungi. We conducted comprehensive mechanistic studies to identify the molecular targets and pathways affected by… read more here.
Keywords: approaches unveil; targeted approaches; unveil cell; cell ... See more keywords
Different Approaches to Unveil Biomolecule Configurations and Their Mutual Interactions
Sign Up to like & getrecommendations! Published in 2020 at "Analytical Letters"
DOI: 10.1080/00032719.2020.1716241
Abstract: Abstract A novel technique was demonstrated that overcomes important drawbacks to crosslink cells by irradiation with ultrashort ultraviolet laser pulses (L-crosslinking). To use this technique coupled to Chromatin ImmunoPrecipitation (ChIP) in a high throughput context,… read more here.
Keywords: biomolecule configurations; mutual interactions; approaches unveil; different approaches ... See more keywords