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   Articles with "approved drug" as a keyword



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The FDA-approved drug ivermectin inhibits the replication of SARS-CoV-2 in vitro

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recommendations! Published in 2020 at "Antiviral Research"

DOI: 10.1016/j.antiviral.2020.104787

Abstract: Abstract Although several clinical trials are now underway to test possible therapies, the worldwide response to the COVID-19 outbreak has been largely limited to monitoring/containment. We report here that Ivermectin, an FDA-approved anti-parasitic previously shown… read more here.

Keywords: ivermectin inhibits; drug ivermectin; approved drug; ivermectin ... See more keywords
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Evaluation of a Pooling Chemoproteomics Strategy with an FDA-Approved Drug Library.

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recommendations! Published in 2022 at "Biochemistry"

DOI: 10.1021/acs.biochem.2c00256

Abstract: Chemoproteomics is a key platform for characterizing the mode of action for compounds, especially for targeted protein degraders such as proteolysis targeting chimeras (PROTACs) and molecular glues. With deep proteome coverage, multiplexed tandem mass tag-mass… read more here.

Keywords: drug library; strategy; strategy fda; approved drug ... See more keywords
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How far are we from an approved drug for nonalcoholic steatohepatitis?

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recommendations! Published in 2023 at "Expert Opinion on Pharmacotherapy"

DOI: 10.1080/14656566.2023.2206953

Abstract: ABSTRACT Introduction Metabolic-associated fatty liver disease (MAFLD) previously known but still debatable, as nonalcoholic fatty liver disease (NAFLD) is one of the main causes of chronic liver disease and subsequent cirrhosis worldwide, accounting for around… read more here.

Keywords: disease; liver disease; mafld nafld; far approved ... See more keywords
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Antimicrobial compounds from an FDA-approved drug library with activity against Streptococcus suis.

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recommendations! Published in 2021 at "Journal of applied microbiology"

DOI: 10.1111/jam.15377

Abstract: AIM Antimicrobial resistance (AMR) has become a global concern. Developing novel antimicrobials is one of the most effective approaches in tackling AMR. Considering its relatively low cost and risk, drug repurposing has been proposed as… read more here.

Keywords: antimicrobial compounds; approved drug; drug; fda approved ... See more keywords