Sensing Adenosine and ATP by Aptamers and Gold Nanoparticles: Opposite Trends of Color Change from Domination of Target Adsorption Instead of Aptamer Binding.
Sign Up to like & getrecommendations! Published in 2020 at "ACS sensors"
DOI: 10.1021/acssensors.0c01169
Abstract: The 27-mer DNA aptamer for adenosine and ATP is a popular model system for designing biosensors. Various strategies have been reported for label-free colorimetric detection using gold nanoparticles (AuNPs). It is generally accepted that free… read more here.
Keywords: adsorption; gold nanoparticles; aptamer binding; target ... See more keywords
A comparative analysis of cell surface targeting aptamers
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DOI: 10.1038/s41467-021-26463-w
Abstract: Aptamers represent a potentially important class of ligands for the development of diagnostics and therapeutics. However, it is often difficult to compare the function and specificity of many of these molecules as assay formats and… read more here.
Keywords: comparative analysis; aptamer binding; cell surface; cell ... See more keywords
Exploring the relationship between aptamer binding thermodynamics, affinity, and specificity
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DOI: 10.1093/nar/gkaf219
Abstract: Abstract Aptamers are oligonucleotide-based bioreceptors that are selected in vitro from randomized libraries to bind specific molecules with high affinity, and are proving popular for applications in diagnostics, bioimaging, and therapeutics. A better understanding of… read more here.
Keywords: aptamer; exploring relationship; thermodynamics; specificity ... See more keywords
Metal and pH-Dependent Aptamer Binding of Tetracyclines Enabling Highly Sensitive Fluorescence Sensing
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DOI: 10.3390/bios12090717
Abstract: Tetracyclines are a widely used group of antibiotics, many of which are currently only used in veterinary medicine and animal husbandry due to their adverse side effects. For the detection of tetracyclines, we previously reported… read more here.
Keywords: binding tetracyclines; dependent aptamer; aptamer binding; metal dependent ... See more keywords