Articles with "aptamer chimera" as a keyword



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A phosphatase-recruiting bispecific antibody-aptamer chimera for enhanced suppression of tumor growth.

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Published in 2023 at "Chemical communications"

DOI: 10.1039/d3cc01137b

Abstract: The development of agents against abnormal activation of receptor tyrosine kinases (RTKs) for therapeutic interventions is in high demand. Using mesenchymal epithelial transition (Met) protein as a proof-of-concept RTK, here we developed a CD148-recruiting bispecific… read more here.

Keywords: aptamer chimera; recruiting bispecific; antibody aptamer; bispecific antibody ... See more keywords