Aptamer-functionalized quantum dots as theranostic nanotools against cancer and bacterial infections: A comprehensive overview of recent trends.
Sign Up to like & getrecommendations! Published in 2023 at "Biotechnology progress"
DOI: 10.1002/btpr.3366
Abstract: Aptamers (Apts) are synthetic nucleic acid ligands that can be engineered to target various molecules, including amino acids, proteins, and pharmaceuticals. Through a series of adsorption, recovery, and amplification steps, Apts are extracted from combinatorial… read more here.
Keywords: quantum dots; functionalized quantum; bacterial infections; cancer bacterial ... See more keywords
Aptamer-Functionalized Fractal Nanoplasmonics-Assisted Laser Desorption/Ionization Mass Spectrometry for Metabolite Detection.
Sign Up to like & getrecommendations! Published in 2022 at "ChemPlusChem"
DOI: 10.1002/cplu.202100479
Abstract: Accurate profiling of metabolites in biofluids provides a feasible approach to disease diagnosis and therapeutic evaluation in clinics. However, current material-based analytical platforms for in vitro metabolite detection often requires tedious sample pretreatment. To address this… read more here.
Keywords: functionalized fractal; assisted laser; laser desorption; desorption ionization ... See more keywords
Aptamer‐Functionalized Barcodes in Herringbone Microfluidics for Multiple Detection of Exosomes
Sign Up to like & getrecommendations! Published in 2022 at "Small Methods"
DOI: 10.1002/smtd.202200236
Abstract: Tumor‐derived exosomes are vital for clinical dynamic and accurate tumor diagnosis, thus developing sensitive and multiple exosomes detection technology has attracted remarkable attention of scientists. Here, a novel herringbone microfluidic device with aptamer‐functionalized barcodes integration… read more here.
Keywords: functionalized barcodes; barcodes herringbone; multiple detection; detection ... See more keywords
Aptamer-functionalized carbon nanomaterials electrochemical sensors for detecting cancer relevant biomolecules
Sign Up to like & getrecommendations! Published in 2018 at "Carbon"
DOI: 10.1016/j.carbon.2017.12.013
Abstract: Abstract As a class of low-dimensional materials, carbon nanomaterials which are mainly composed of sp2 and sp3 carbon atoms arranged into a seamless network have aroused considerable interest since the first exploration of fullerene by… read more here.
Keywords: electrochemical sensors; carbon; carbon nanomaterials; cancer relevant ... See more keywords
A novel theranostic system of AS1411 aptamer-functionalized albumin nanoparticles loaded on iron oxide and gold nanoparticles for doxorubicin delivery.
Sign Up to like & getrecommendations! Published in 2019 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2019.04.025
Abstract: Recently DNA aptamers have attracted remarkable attention as possible targeting ligands since selective targeting of cancer cells is a critical step in cancer diagnosis and therapy. Here, the development of AS1411 aptamer-functionalized albumin nanoparticles loaded… read more here.
Keywords: aptamer functionalized; as1411 aptamer; gold nanoparticles; iron oxide ... See more keywords
Preparation and application of aptamer-functionalized sorbent for the analysis of ultra-trace aflatoxin M1 and analogues in milk
Sign Up to like & getrecommendations! Published in 2021 at "Microchemical Journal"
DOI: 10.1016/j.microc.2021.106179
Abstract: Abstract A novel, efficient and specific aptamer-functionalized sorbent was successfully synthesized and applied in the analysis of ultra-trace aflatoxin M1 (AFM1) and its analogues in milk. By using a gold nanoparticle-based colorimetric analysis tool, we… read more here.
Keywords: functionalized sorbent; analogues milk; ultra trace; aptamer functionalized ... See more keywords
Engineering of An Aptamer-Functionalized Fluorescent DNA Sensor for Cu(II) Responding in Living Tumor Cells.
Sign Up to like & getrecommendations! Published in 2023 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.3c01008
Abstract: Copper ions play vital roles in regulating life processes and being closely involved in several diseases such as cancer. Although detection methods based on fluorescent sensors or other strategies have been developed, it still remains… read more here.
Keywords: dna; detection; sensor; aptamer functionalized ... See more keywords
A Chemiluminescence Sensor for the Detection of α-Fetoprotein and Carcinoembryonic Antigen Based on Dual-Aptamer Functionalized Magnetic Silicon Composite.
Sign Up to like & getrecommendations! Published in 2023 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.3c01056
Abstract: In this work, a dual-aptamer functionalized magnetic silicon composite was prepared and used to construct a chemiluminescence (CL) sensor for the detection of α-fetoprotein (AFP) and carcinoembryonic antigen (CEA). First, SiO2@Fe3O4 was prepared, and polydiallyl… read more here.
Keywords: dual aptamer; detection; cea; sensor ... See more keywords
Aptamer-Functionalized Granzyme B-Responsive Nanoprobe for Immunotherapy Assessment: Real-Time Monitoring of Cytotoxic T Lymphocyte Activation Cleavage.
Sign Up to like & getrecommendations! Published in 2025 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.5c03155
Abstract: Real-time visualization of immune effector functions remains pivotal for advancing cancer immunotherapy. However, most existing molecular probes are hindered by limited sensitivity and specificity due to their "always on" signals and the absence of targeted… read more here.
Keywords: real time; immunotherapy; nanoprobe; activation ... See more keywords
Aptamer-Functionalized and Gold Nanoparticle Array-Decorated Magnetic Graphene Nanosheets Enable Multiplexed and Sensitive Electrochemical Detection of Rare Circulating Tumor Cells in Whole Blood.
Sign Up to like & getrecommendations! Published in 2019 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.9b02403
Abstract: The identification and monitoring of circulating tumor cells (CTCs) in human blood has a pivotal role for the convenient diagnosis of different cancers. However, it remains a major challenge to monitor these CTCs because of… read more here.
Keywords: detection; tumor cells; circulating tumor; blood ... See more keywords
Aptamer-Functionalized Upconverting Nanoformulations for Light-Switching Cancer-Specific Recognition and In Situ Photodynamic-Chemo Sequential Theranostics.
Sign Up to like & getrecommendations! Published in 2020 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.0c14730
Abstract: Biomarker-activatable theranostic formulations offer the potential for removing specific tumors with a high diagnostic accuracy and a significant pharmacological effect. Herein, we developed a novel activatable theranostic nanoformulation UAS-PD [upconversion nanophosphor (UCNP)-aptamer/ssDNA-pyropheophorbide-a (PPA)-doxyrubicin (DOX)], which… read more here.
Keywords: upconverting nanoformulations; cancer cells; nanoformulations light; functionalized upconverting ... See more keywords