Aptamer-siRNA chimera and gold nanoparticle modified collagen membrane for the treatment of malignant pleural effusion
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2022.973892
Abstract: Malignant pleural effusion is one of the most common complications of advanced lung cancer and there is no effective clinical treatment at present. Here, we constructed an aptamer-siRNA chimeras/PEI/PEG/gold nanoparticle (AuNP)/collagen membrane that can progressively… read more here.
Keywords: aptamer sirna; pleural effusion; malignant pleural; collagen membrane ... See more keywords
Aptamer-siRNA Chimeras: Discovery, Progress, and Future Prospects
Sign Up to like & getrecommendations! Published in 2017 at "Biomedicines"
DOI: 10.3390/biomedicines5030045
Abstract: Synthetic nucleic acid ligands (aptamers) have emerged as effective delivery tools for many therapeutic oligonucleotide-based drugs, including small interfering RNAs (siRNAs). In this review, we summarize recent progress in the aptamer selection technology that has… read more here.
Keywords: sirna chimeras; prospects aptamer; progress; aptamer sirna ... See more keywords