Bioinspired molecular engineering of bivalent aptamers by ligand-induced self-dimerization.
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DOI: 10.1039/d2cc05799a
Abstract: A bioinspired "point-and-shoot" molecular strategy is described for engineering noncovalent aptamers via K+-induced reassembly of a split G-quadruplex sequence at the end of monomeric aptamers. This design compensates for insufficient cell recognition of monovalent aptamers… read more here.
Keywords: bivalent aptamers; molecular engineering; bioinspired molecular; aptamers ligand ... See more keywords