Articles with "aptamers optimized" as a keyword



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Selection of 2'-Fluoro-Modified Aptamers with Optimized Properties.

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Published in 2017 at "Journal of the American Chemical Society"

DOI: 10.1021/jacs.6b13132

Abstract: RNA or single-stranded DNA aptamers with 2'-F pyrimidines have been pursued to increase resistance to nucleases, and while it seems likely that these and other modifications, including the modification of purines, could be used to… read more here.

Keywords: modified aptamers; aptamers optimized; fluoro modified; selection fluoro ... See more keywords