RNA aptamers targeted for human αA-crystallin do not bind αB-crystallin, and spare the α-crystallin domain.
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DOI: 10.1016/j.bbrc.2017.07.085
Abstract: The molecular chaperones, α-crystallins, belong to the small heat shock protein (sHSP) family and prevent the aggregation and insolubilization of client proteins. Studies in vivo have shown that the chaperone activity of the α-crystallins is raised… read more here.
Keywords: bind; rna aptamers; aptamers targeted; crystallin ... See more keywords