Identifying false-positive chlamydia and gonorrhea results using nonmanufacturer relative light unit cutoffs for the Aptima Combo 2 Assay.
Sign Up to like & getrecommendations! Published in 2025 at "American journal of clinical pathology"
DOI: 10.1093/ajcp/aqaf085
Abstract: OBJECTIVE Chlamydia trachomatis and Neisseria gonorrhoeae present substantial public health challenges. Accurate diagnostic testing is essential to prevent misdiagnosis and unnecessary treatment. Although nucleic acid amplification tests offer excellent performance, they are not infallible. This… read more here.
Keywords: combo assay; aptima combo; relative light; trachomatis ... See more keywords
Chlamydia trachomatis variants escaping detection in the Aptima Combo 2® assay in the United States.
Sign Up to like & getrecommendations! Published in 2022 at "Sexually transmitted diseases"
DOI: 10.1097/olq.0000000000001617
Abstract: BACKGROUND The Aptima Combo 2® (AC2) assay manufactured by Hologic, Inc. detects Neisseria gonorrhoeae (NG) and/or Chlamydia trachomatis (CT) in urogenital and extragenital specimens by targeting either a 16S rRNA (NG) or 23S rRNA (CT)… read more here.
Keywords: aptima combo; ac2 assay; chlamydia trachomatis; 23s rrna ... See more keywords