Diagnosis and management of new onset severe coagulopathy during after‐hours with thromboelastography
Sign Up to like & getrecommendations! Published in 2021 at "American Journal of Hematology"
DOI: 10.1002/ajh.26435
Abstract: On a Friday evening, a 54-year-old man with celiac disease presented to the emergency department following 6 days of right arm and leg pain with swelling, which limited his ambulation. He also noted an enlarging… read more here.
Keywords: time; mixing study; patient; aptt ... See more keywords
Anticoagulant Effects of Dabigatran on Coagulation Laboratory Parameters in Pediatric Patients: Combined Data from Five Pediatric Clinical Trials
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DOI: 10.1055/s-0042-1744542
Abstract: Background Dabigatran etexilate, a direct oral thrombin inhibitor, is approved to treat venous thromboembolism (VTE) in both adults and children. Objectives This population analysis characterized relationships between dabigatran total plasma concentrations and coagulation laboratory parameters… read more here.
Keywords: laboratory; dabigatran; laboratory parameters; coagulation laboratory ... See more keywords
Haematological variables and risk of future venous thromboembolism in the British Regional Heart Study on men. Combined D‐dimer and APTT as a predictive test for thromboembolism?
Sign Up to like & getrecommendations! Published in 2022 at "British Journal of Haematology"
DOI: 10.1111/bjh.18288
Abstract: We examined the associations between haematological and inflammatory variables with future venous thromboembolism (VTE), in 3494 men aged 60–79 years, with no previous history of VTE or myocardial infarction, who were not receiving oral anticoagulants. After… read more here.
Keywords: future venous; dimer; vte; risk ... See more keywords
In vitro anticoagulant activity of selected medicinal plants: potential interactions with warfarin and development of new anticoagulants
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DOI: 10.1515/jbcpp-2021-0079
Abstract: Abstract Objectives Warfarin is the most widely used anticoagulant in the world, but it has several limitations including its narrow therapeutic range, need for dose adjustment and high potential for interactions. The simultaneous use of… read more here.
Keywords: anticoagulant activity; vitro anticoagulant; medicinal plants; potential interactions ... See more keywords
The First Korean Case of High-Molecular-Weight Kininogen Deficiency, With a Novel Variant, c.488delG, in the KNG1 Gene
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DOI: 10.3343/alm.2020.40.3.264
Abstract: Dear Editor, High-molecular-weight kininogen (HK) circulates bound to prekallikrein (PK), which can bind to negatively charged phospholipids. It is a non-enzymatic cofactor for kallikrein binding to negatively charged phospholipids. Kallikrein activates factor XII, which then… read more here.
Keywords: weight kininogen; high molecular; molecular weight; aptt prolongation ... See more keywords