Laxative effect of repeated Daiokanzoto is attributable to decrease in aquaporin-3 expression in the colon
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Natural Medicines"
DOI: 10.1007/s11418-018-1174-1
Abstract: Daiokanzoto (DKT) exerts its laxative effect via colonic inflammation caused by sennoside A in Daio (rhubarb). Previously, we showed that the laxative effect of sennoside A is related to decreased aquaporin-3 (AQP3) expression in mucosal… read more here.
Keywords: aqp3 expression; effect repeated; laxative effect; effect ... See more keywords
Time for a change
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DOI: 10.1111/bjd.20867
Abstract: responsible for most of the skin damage associated with photoageing, including specific histone acetylation changes. Recent research has further confirmed that inhibition of histone deacetylases is an effective approach for modulating expression of this water… read more here.
Keywords: aqp3 expression; expression; model; autophagy ... See more keywords
Tumor necrosis factor α decreases aquaporin 3 expression in intestinal epithelial cells through inhibition of constitutive transcription
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DOI: 10.14814/phy2.13451
Abstract: Inflammatory diseases of the gut are associated with altered electrolyte and water transport, leading to the development of diarrhea. Epithelially expressed aquaporins (AQPs) are downregulated in inflammation, although the mechanisms involved are not known. We… read more here.
Keywords: epithelial cells; aqp3 expression; intestinal epithelial; expression intestinal ... See more keywords
High Levels of Tumor Necrosis Factor-Alpha Reduce Placental Aquaporin 3 Expression and Impair in vitro Trophoblastic Cell Migration
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2021.696495
Abstract: Placentas from preeclamptic women display augmented tumor necrosis factor-alpha (TNF-α) levels with reduced expression of aquaporin 3 (AQP3). However, whether TNF-α modulates AQP3 expression remains to be elucidated. We hypothesize that elevated levels of TNF-α… read more here.
Keywords: cell migration; aqp3 expression; expression; tnf ... See more keywords