Seizures and Encephalitis in Myelin Oligodendrocyte Glycoprotein IgG Disease vs Aquaporin 4 IgG Disease
Sign Up to like & getrecommendations! Published in 2018 at "JAMA Neurology"
DOI: 10.1001/jamaneurol.2017.3196
Abstract: Importance Antibodies to myelin oligodendrocyte glycoprotein IgG (MOG-IgG) are increasingly detected in patients with non–multiple sclerosis–related demyelination, some of whom manifest a neuromyelitis optica (NMO) phenotype. Cortical involvement, encephalopathy, and seizures are rare in aquaporin… read more here.
Keywords: igg disease; mog igg; igg positive; disease ... See more keywords
Clinical, Radiologic, and Prognostic Features of Myelitis Associated With Myelin Oligodendrocyte Glycoprotein Autoantibody
Sign Up to like & getrecommendations! Published in 2018 at "JAMA Neurology"
DOI: 10.1001/jamaneurol.2018.4053
Abstract: Importance Recognizing the characteristics of myelin oligodendrocyte glycoprotein autoantibody (MOG-IgG) myelitis is essential for early accurate diagnosis and treatment. Objective To evaluate the clinical, radiologic, and prognostic features of MOG-IgG myelitis and compare with myelitis… read more here.
Keywords: aqp4 igg; mog igg; myelitis; igg myelitis ... See more keywords
Factors for Rituximab Refractoriness in AQP4‐IgG+ NMOSD: A Cohort Study
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DOI: 10.1002/acn3.70095
Abstract: Neuromyelitis optica spectrum disorder (NMOSD) is a severe autoimmune condition of the central nervous system (CNS), often associated with aquaporin‐4 antibodies (AQP4‐IgG). Rituximab, a CD20+ B‐cell depleting monoclonal antibody, is widely used as first‐line therapy.… read more here.
Keywords: rituximab refractoriness; aqp4 igg; factors rituximab; refractoriness aqp4 ... See more keywords
Comparing the efficacy of efgartigimod and intravenous immunoglobulin on AQP4‐IgG‐positive neuromyelitis optica spectrum disorder during acute attacks
Sign Up to like & getrecommendations! Published in 2025 at "British Journal of Clinical Pharmacology"
DOI: 10.1002/bcp.70190
Abstract: The aim of our study was to evaluate the efficacy of efgartigimod and intravenous immunoglobulin (IVIG) on AQP4‐IgG‐positive neuromyelitis optica spectrum disorder (NMOSD) patients during acute attacks. read more here.
Keywords: intravenous immunoglobulin; efgartigimod intravenous; positive neuromyelitis; igg positive ... See more keywords
[From neuromyelitis optica to neuromyelitis optica spectrum disorder: from clinical syndrome to diagnistic classification].
Sign Up to like & getrecommendations! Published in 2021 at "Der Nervenarzt"
DOI: 10.1007/s00115-021-01098-w
Abstract: Neuromyelitis optica spectrum disorder (NMOSD), derived from NMO or Devic's disease, is considered as a distinct disease since the discovery of a novel and pathogenic serum autoantibody targeting aquaporin‑4 (AQP4-IgG) and is distinguished from classical multiple sclerosis… read more here.
Keywords: neuromyelitis; spectrum disorder; neuromyelitis optica; optica spectrum ... See more keywords
Vision Prognosis and Associated Factors of Optic Neuritis in Dependence of Glial Autoimmune Antibodies.
Sign Up to like & getrecommendations! Published in 2022 at "American journal of ophthalmology"
DOI: 10.1016/j.ajo.2022.01.015
Abstract: PURPOSE To assess the visual prognosis of optic neuritis (ON) in dependence of the glial autoimmune antibody status and associated factors. DESIGN Longitudinal observational cohort study METHODS: : Patients with ON and measurements of serum… read more here.
Keywords: igg; group; vision; mog igg ... See more keywords
Lack of association between unipolar or bipolar depression and serum aquaporin-4 autoantibodies
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DOI: 10.1016/j.bbi.2020.05.001
Abstract: Aquaporin-4 (AQP4), an astrocyte water channel protein, is the target antigen of serum immunoglobulin G (IgG) autoantibody in neuromyelitis optica spectrum disorders (NMOsd), a group of inflammatory, demyelinating diseases of the central nervous system. Recently,… read more here.
Keywords: depression; aqp4; serum; unipolar bipolar ... See more keywords
Serum AQP4-IgG level is associated with the phenotype of the first attack in neuromyelitis optica spectrum disorders
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Neuroimmunology"
DOI: 10.1016/j.jneuroim.2020.577168
Abstract: We aimed in this study to elucidate the impact of serum AQP4-IgG titer before starting treatments to the clinical manifestation of neuromyelitis optica spectrum disorders (NMOSD). Serum titer at the onset, measured using live cell-based… read more here.
Keywords: spectrum disorders; neuromyelitis optica; first attack; optica spectrum ... See more keywords
Prolonged B-cell depletion after rituximab in AQP4-IgG-positive neuromyelitis optica spectrum disorder
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Neuroimmunology"
DOI: 10.1016/j.jneuroim.2021.577666
Abstract: Rituximab (a B-cell depleting monoclonal antibody) is increasingly utilized for treatment of different immune-mediated neurologic disorders, including aquaporin-4-IgG-positive neuromyelitis optica spectrum disorder (AQP4-IgG-NMOSD). After an initial treatment course, the drug is generally reinfused when peripheral… read more here.
Keywords: rituximab; cell depletion; igg positive; cell ... See more keywords
Patient-reported burden of symptoms in neuromyelitis optica: A secondary analysis on pain and quality of life
Sign Up to like & getrecommendations! Published in 2021 at "Journal of the Neurological Sciences"
DOI: 10.1016/j.jns.2021.117546
Abstract: INTRODUCTION Relapses of neuromyelitis optica spectrum disorder (NMOSD) result in cumulative neurologic disabilities, are unpredictable, and are interspersed with remissions. Pain in NMOSD is often severe and intractable, with a significant impact on patient quality… read more here.
Keywords: neuromyelitis optica; quality life; aqp4 igg; pain ... See more keywords
Pruritus in neuromyelitis optica spectrum disorders and multiple sclerosis
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Neuroscience"
DOI: 10.1016/j.jocn.2020.07.022
Abstract: PURPOSE Differential diagnosis between neuromyelitis optica spectrum disorders (NMOSD) and multiple sclerosis (MS) at early stage remains challenging at present. Pruritus is reported as a common or specific feature in NMOSD with serum aquaporin-4 immunoglobulin… read more here.
Keywords: nmosd patients; spectrum disorders; pruritus; neuromyelitis optica ... See more keywords