Comparative analysis of cytokine profiles of glaucomatous tears and aqueous humour reveals potential biomarkers for trabeculectomy complications
Sign Up to like & getrecommendations! Published in 2019 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.12637
Abstract: Glaucoma is a multifactorial neurodegenerative disease that causes impaired vision and, in advanced cases, blindness. The increasing prevalence of glaucoma due to an ageing population has necessitated the identification of suitable biomarkers for the early… read more here.
Keywords: comparative analysis; profiles glaucomatous; humour; analysis cytokine ... See more keywords
Early local activation of complement in aqueous humour of patients with age-related macular degeneration
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DOI: 10.1038/s41433-019-0501-4
Abstract: To investigate complement activation in aqueous humour of patients with early, intermediate and neovascular age-related macular degeneration (AMD). Aqueous humour of 79 AMD patients (early, intermediate and neovascular) and 77 age-matched controls was prospectively collected.… read more here.
Keywords: age; complement; amd patients; activation ... See more keywords
Detection of Proteins Associated with Extracellular Matrix Regulation in the Aqueous Humour of Patients with Primary Glaucoma
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DOI: 10.1080/02713683.2019.1608261
Abstract: ABSTRACT Purpose: The protein composition of aqueous humour (AH) has held significant relevance and remains to be the prime sample in the discovery of biomarkers in glaucoma. The purpose of this study is to analyze… read more here.
Keywords: protein; poag; control; extracellular matrix ... See more keywords
Elevated intraocular pressure increases melatonin levels in the aqueous humour
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DOI: 10.1111/aos.13253
Abstract: To study the levels of melatonin in the aqueous humour of normotensive and hypertensive intraocular pressure (IOP) patients and to compare them to an animal model of glaucoma. read more here.
Keywords: intraocular pressure; increases melatonin; elevated intraocular; pressure increases ... See more keywords
Ocular penetration of oral acetaminophen in horses.
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DOI: 10.1111/evj.13902
Abstract: BACKGROUND Acetaminophen (paracetamol) is increasingly used to treat painful conditions in horses but its ocular penetration has not been studied. OBJECTIVES To determine whether orally administered acetaminophen penetrates the aqueous humour of the normal equine… read more here.
Keywords: acetaminophen; ocular penetration; aqueous humour; humour serum ... See more keywords
Concentrations of glucose metabolites in the aqueous humour of diabetic cataract eyes.
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DOI: 10.1177/11206721231156496
Abstract: PURPOSE Glucose metabolism underpins diabetic cataracts (DCs), but the relationship between the two remains unclear. Here, we tested the aqueous humour (AH) of patients with DCs to elucidate glucose metabolite levels. METHODS In this study,… read more here.
Keywords: metabolism; glucose pyruvate; concentrations glucose; glucose metabolism ... See more keywords
Effect of peripheral iridectomy on VEGF-A and TGF-β levels in rabbit aqueous humour
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DOI: 10.1186/s12886-022-02249-6
Abstract: Background Peripheral iridectomy (PI), routinely performed during glaucoma filtration surgery, may contribute to scarring. This study aims to determine whether PI alters the concentrations of VEGF-A and TGF-β isoforms in the rabbit aqueous humour. Methods… read more here.
Keywords: rabbit aqueous; tgf tgf; peripheral iridectomy; tgf ... See more keywords
Aqueous humour proteins and treatment outcomes of anti-VEGF therapy in neovascular age-related macular degeneration
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DOI: 10.1371/journal.pone.0229342
Abstract: We aimed to construct a better model for predicting treatment outcomes of anti-vascular endothelial growth factor therapy for neovascular age-related macular degeneration (nAMD) using the concentrations of aqueous humour proteins at baseline and during treatment.… read more here.
Keywords: treatment outcomes; treatment; outcomes anti; coefficient ... See more keywords