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Published in 2017 at "Flavour and Fragrance Journal"
DOI: 10.1002/ffj.3395
Abstract: Essential oils (EOs) and their individual components have several biological properties and are used in cosmetics, food and pharmaceutical industries. However, their application still presents a challenge owing mainly to their volatility and their poor…
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Keywords:
aqueous solubility;
captisol efficient;
carrier;
solubility ... See more keywords
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Published in 2020 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2020.119812
Abstract: Poor aqueous solubility of terpenophenolic compound Cannabidiol (CBD) is a major issue in the widespread use of this promising therapeutic polyphenol. Moreover, choosing the appropriate strategy to overcome this challenge is time-consuming and based on…
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Keywords:
cbd;
aqueous solubility;
solubility enhancement;
solubility ... See more keywords
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Published in 2020 at "Lwt - Food Science and Technology"
DOI: 10.1016/j.lwt.2020.110078
Abstract: Abstract There is a need to have functional protein-rich ingredients to formulate a range of vegan and vegetarian products. However, available proteins vary in functionality and in particular in solubility, even if derived from the…
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Keywords:
protein powders;
plant;
aqueous solubility;
appearance ... See more keywords
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Published in 2020 at "Journal of pharmaceutical sciences"
DOI: 10.1016/j.xphs.2020.10.012
Abstract: The solubility of bortezomib, a boronic acid, in water and normal saline is often misquoted in the literature. Here we confirm that bortezomib equilibrium solubility in water and normal saline is 0.59 ± 0.07 and…
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Keywords:
presence;
mannitol;
aqueous solubility;
formulation ... See more keywords
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Published in 2022 at "ACS Omega"
DOI: 10.1021/acsomega.2c00642
Abstract: Determining the aqueous solubility of molecules is a vital step in many pharmaceutical, environmental, and energy storage applications. Despite efforts made over decades, there are still challenges associated with developing a solubility prediction model with…
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Keywords:
solubility prediction;
solubility;
prediction;
aqueous solubility ... See more keywords
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Published in 2022 at "ACS Omega"
DOI: 10.1021/acsomega.2c03885
Abstract: Aqueous solubility is one of the most important physicochemical properties in drug discovery. At present, the prediction of aqueous solubility of compounds is still a challenging problem. Machine learning has shown great potential in solubility…
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Keywords:
solubility compounds;
prediction aqueous;
solubility;
light gradient ... See more keywords
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Published in 2019 at "Communications Chemistry"
DOI: 10.1038/s42004-018-0100-5
Abstract: Peptides and small proteins are attractive therapeutic candidates due to their inherent selectivity and limited off-target effects. Unfortunately, their potential is often hindered by unfavorable physicochemical properties. This is particularly true in the case of…
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Keywords:
glucagon;
aqueous solubility;
therapeutic peptides;
stereochemical inversion ... See more keywords
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Published in 2019 at "Chemical Engineering Communications"
DOI: 10.1080/00986445.2019.1691539
Abstract: Abstract The data of aqueous solubility of starch are essential for the determination of appropriate uses of starch and design of starch based food products. Unfortunately, these data are scarce and often, some are inconsistent.…
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Keywords:
botanical sources;
flory huggins;
aqueous solubility;
various botanical ... See more keywords
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Published in 2017 at "Pharmaceutical Development and Technology"
DOI: 10.1080/10837450.2016.1193193
Abstract: Abstract In the present study, a lyophilized milk-based solid dispersion (SD) of ritonavir (RTV) was developed with the goal of improving its aqueous solubility. The SD was prepared by lyophilization, and characterized for its physicochemical…
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Keywords:
rtv;
aqueous solubility;
formulation;
lyophilized milk ... See more keywords
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Published in 2021 at "Briefings in bioinformatics"
DOI: 10.1093/bib/bbaa092
Abstract: Aqueous solubility is the key property driving many chemical and biological phenomena and impacts experimental and computational attempts to assess those phenomena. Accurate prediction of solubility is essential and challenging, even with modern computational algorithms.…
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Keywords:
molecule;
different molecular;
aqueous solubility;
deep learning ... See more keywords
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Published in 2017 at "Journal of Food Process Engineering"
DOI: 10.1111/jfpe.12407
Abstract: Abstract Xanthone has low aqueous solubility, thus limiting its food application. The aim of this study is to increase aqueous solubility of xanthone through spray drying xanthone in fish oil with maltodextrin and gum Arabic.…
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Keywords:
aqueous solubility;
spray;
spray dried;
dried xanthone ... See more keywords