Aqueous Wittig reaction-mediated fast fluorogenic identification and single-base resolution analysis of 5-formylcytosine in DNA.
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DOI: 10.1039/d0cc04950f
Abstract: A highly reactive ylide tBuA was introduced, which could react rapidly with the 5-formyl and 4-amino groups of 5-formylcytosine (5fC) under mild conditions without any co-solvent or catalyst in a manner of Wittig olefination and… read more here.
Keywords: aqueous wittig; base resolution; single base; dna ... See more keywords