Exploratory immunogenicity outcomes of peanut oral immunotherapy: Findings from the PALISADE trial
Sign Up to like & getrecommendations! Published in 2024 at "Clinical and Translational Allergy"
DOI: 10.1002/clt2.12326
Abstract: Abstract Background Immunoglobulin E (IgE) and immunoglobulin G4 (IgG4) to peanut and its components may influence the clinical reactivity to peanut. Allergen‐specific immunotherapy is known for modifying both IgE and IgG4. Peanut oral immunotherapy may… read more here.
Keywords: igg4; ige igg4; peanut; immunotherapy ... See more keywords
Effect of high-moisture extrusion and addition of transglutaminase on major peanut allergens content extracted by three step sequential method.
Sign Up to like & getrecommendations! Published in 2022 at "Food chemistry"
DOI: 10.1016/j.foodchem.2022.132569
Abstract: The effect of high-moisture extrusion (HME) with or without transglutaminase (TGase) on peanut allergen levels and their extractability was studied. A three-stage sequential protein extraction significantly improved the protein recovery in processed samples (extrudate meat… read more here.
Keywords: ara ara; high moisture; effect high; moisture extrusion ... See more keywords
Ara h 1 and Ara h 6 Sensitization Causes Clinical Peanut Allergy in Ara h 2-Negative Individuals
Sign Up to like & getrecommendations! Published in 2018 at "International Archives of Allergy and Immunology"
DOI: 10.1159/000493327
Abstract: Background: Of the major peanut allergens, sensitivity to Ara h 2 has the highest prediction for clinical allergy. In this study, we evaluated sensitization to peanut components in Iceland and related Ara h 2-negative sensitization… read more here.
Keywords: ara negative; ara; ara ara; peanut ... See more keywords
Peanut Allergy in Spanish Children: Comparative Profile of Peanut Allergy versus Tolerance
Sign Up to like & getrecommendations! Published in 2019 at "International Archives of Allergy and Immunology"
DOI: 10.1159/000495579
Abstract: Background: Peanut storage proteins (Ara h 1, Ara h 2, and Ara h 3) have been described as the major peanut allergens in children, although not all peanut-sensitized individuals have clinical reactivity after exposure. Objectives:… read more here.
Keywords: peanut storage; ara ara; peanut allergic; peanut ... See more keywords
Peanut lipids influence the response of bronchial epithelial cells to the peanut allergens Ara h 1 and Ara h 2 by decreasing barrier permeability
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2023.1126008
Abstract: Background: Peanut-allergic individuals react upon their first known ingestion of peanuts, suggesting sensitization occurs through non-oral exposure. Increasing evidence suggests that the respiratory tract is a probable site for sensitization to environmental peanuts. However, the… read more here.
Keywords: bronchial epithelial; ara ara; peanut allergens; peanut lipids ... See more keywords
Electrochemical Immunosensor for the Simultaneous Determination of Two Main Peanut Allergenic Proteins (Ara h 1 and Ara h 6) in Food Matrices
Sign Up to like & getrecommendations! Published in 2021 at "Foods"
DOI: 10.3390/foods10081718
Abstract: Efficiently detecting peanut traces in food products can prevent severe allergic reactions and serious health implications. This work presents the development of an electrochemical dual immunosensor for the simultaneous analysis of two major peanut allergens,… read more here.
Keywords: immunosensor simultaneous; ara ara; food matrices; peanut ... See more keywords
The Role of Pyrazolopyridine Derivatives on Different Steps of Herpes Simplex Virus Type-1 In Vitro Replicative Cycle
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23158135
Abstract: Herpes simplex virus type-1 (HSV-1) infection causes several disorders, and acyclovir is used as a reference compound. However, resistant strains are commonly observed. Herein, we investigate the effects of N-heterocyclic compounds (pyrazolopyridine derivatives), named ARA-04,… read more here.
Keywords: cycle; ara ara; ara; simplex virus ... See more keywords
Release of Major Peanut Allergens from Their Matrix under Various pH and Simulated Saliva Conditions—Ara h2 and Ara h6 Are Readily Bio-Accessible
Sign Up to like & getrecommendations! Published in 2018 at "Nutrients"
DOI: 10.3390/nu10091281
Abstract: The oral mucosa is the first immune tissue that encounters allergens upon ingestion of food. We hypothesized that the bio-accessibility of allergens at this stage may be a key determinant for sensitization. Light roasted peanut… read more here.
Keywords: ara readily; ara; peanut allergens; ara ara ... See more keywords
Viral Vector Based Immunotherapy for Peanut Allergy
Sign Up to like & getrecommendations! Published in 2024 at "Viruses"
DOI: 10.3390/v16071125
Abstract: Food allergy (FA) is estimated to impact up to 10% of the population and is a growing health concern. FA results from a failure in the mucosal immune system to establish or maintain immunological tolerance… read more here.
Keywords: vector; peanut allergy; peanut; immunotherapy ... See more keywords