9-(2′-Deoxy-2′-Fluoro-β-d-Arabinofuranosyl) Adenine Is a Potent Antitrypanosomal Adenosine Analogue That Circumvents Transport-Related Drug Resistance
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DOI: 10.1128/aac.02719-16
Abstract: ABSTRACT Current chemotherapy against African sleeping sickness, a disease caused by the protozoan parasite Trypanosoma brucei, is limited by toxicity, inefficacy, and drug resistance. Nucleoside analogues have been successfully used to cure T. brucei-infected mice,… read more here.
Keywords: drug resistance; deoxy fluoro; fluoro arabinofuranosyl; arabinofuranosyl adenine ... See more keywords