Unraveling the mechanism of arbidol binding and inhibition of SARS-CoV-2: Insights from atomistic simulations
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DOI: 10.1016/j.ejphar.2020.173836
Abstract: The COVID-19 pandemic has spread rapidly and posed an unprecedented threat to the global economy and human health. Broad-spectrum antivirals are currently being administered to treat severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). China's prevention… read more here.
Keywords: rbd ace2; inhibition; arbidol; sars cov ... See more keywords
Simulation of Molecular Dynamics of SARS-CoV-2 S-Protein in the Presence of Multiple Arbidol Molecules: Interactions and Binding Mode Insights
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DOI: 10.3390/v14010119
Abstract: In this work, we evaluated the antiviral activity of Arbidol (Umifenovir) against SARS-CoV-2 using a pseudoviral system with the glycoprotein S of the SARS-CoV-2 virus on its surface. In order to search for binding sites… read more here.
Keywords: cov protein; dynamics sars; molecular dynamics; simulation molecular ... See more keywords