MSK1 regulates transcriptional induction of Arc/Arg3.1 in response to neurotrophins
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DOI: 10.1002/2211-5463.12232
Abstract: The immediate early gene activity‐regulated cytoskeletal protein (Arc)/Arg3.1 and the neurotrophin brain‐derived neurotrophic factor (BDNF) play important roles in synaptic plasticity and learning and memory in the mammalian brain. However, the mechanisms by which BDNF… read more here.
Keywords: msk1; arc arg3; factor; response ... See more keywords
Glutamate-induced rapid induction of Arc/Arg3.1 requires NMDA receptor-mediated phosphorylation of ERK and CREB
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DOI: 10.1016/j.neulet.2017.09.024
Abstract: Arc/Arg3.1 is a unique immediate early gene whose expression is highly dynamic and correlated with various forms of synaptic plasticity. Many previous reports highlight the complexity of mechanisms that regulate Arc/Arg3.1 expression in neurons. In… read more here.
Keywords: arc arg3; glutamate induced; arg3 protein; arc ... See more keywords
Activity-regulated cytoskeleton-associated protein/activity-regulated gene 3.1 (Arc/Arg3.1) enhances dendritic cell vaccination in experimental melanoma
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DOI: 10.1080/2162402x.2021.1920739
Abstract: ABSTRACT Dendritic cell (DC) vaccination has proven to be an effective and safe adjuvant for cancer immunotherapies. As the presence of DCs within the tumor microenvironment promotes adaptive antitumor immunity, enhancement of DC migration toward… read more here.
Keywords: vaccination; activity regulated; tumor; cell ... See more keywords